79154-56-6

Upstream product

• 79154-57-7 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-N₆-benzoyladenosine 
• 72351-28-1 2-chlorophenyl phosphordi(1H-1-[1,2,4]triazolide) 
• 4546-55-8 N-benzoyladenosine 
• 18043-71-5 1,1,3,3-tetraisopropyldisiloxane 
• 121768-15-8 3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-N⁽⁶⁾-benzoyladenosine-2' (2-chlorophenyl) Phosphoro-(1,2,4-triazolidate) 

Downstream Products

• 79177-50-7 C₉₁H₁₁₃Cl₂N₁₅O₂₄P₂Si₄ 
• 136315-01-0 3'-O-(1,1,3,3-tetraisopropyldisiloxane-1-yl)-N⁽⁶⁾-benzoyladenosine-2' (2-chlorophenyl) (2-cyanoethyl) phosphate 
• 58-61-7 adenosine 
• 121768-17-0 C₇₀H₉₄Cl₂N₁₀O₁₈P₂Si₄*C₆H₁₅N 
• 79154-54-4 C₅₆H₆₆ClN₁₀O₁₅PSi₂ 

Relevant academic research and scientific papers

SYNTHESIS OF 2'-END LIPOPHILIZED DERIVATIVES OF 2',5'-TRIADENYLATES

Synthesis of protected derivatives of 2 - 5 A3 core starting from 2',3'-O-ethoxymethylene-N6-benzoyladenosine (I) by triazolidate and/or modified triester method are described.Preparation of adenylyl-(2'-5')-adenylyl-(2'-5')-2',3'-O-(1-methoxyhexadecylidene)adenosine (X), adenylyl-(2'-5')-adenylyl-(2'-5')-2'(3')-O-palmitoyladenosine (XIII) and 5'-phosphoryladenyl-(2'-5')-adenylyl-(2'-5')-2',3'-O-(1-methoxyhexadecylidene)adenosine (XVI) are described.

THE TETRAISOPROPYLDISILOXANE-1,3-DIYL: A VERSATILE PROTECTING GROUP FOR THE SYNTHESIS OF ADENYLYL-(2'->5')-ADENYLYL-(2'->5')-ADENOSINE (2-5A CORE).

A2'p5'A2'p5'A has been synthesised in large scale using 3',5'-tetraisopropyldisilyl-6-N-benzoyl adenosine as the starting material.