79208-79-0Relevant academic research and scientific papers
Unexpected 1,3-oxazolidine formation in the attempted oxidation of N- aryl-N-methyl substituted β-amino alcohols using pyridinium dichromate
Yli-Kauhaluoma, Jari T.,Harwig, Curtis W.,Wentworth Jr., Paul,Janda, Kim D.
, p. 2269 - 2272 (1998)
1,3-Oxazolidines were obtained from the reaction of N-methyl substituted β-amino alcohols with pyridinium dichromate in dichloromethane. A single electron transfer mechanism, SET, is proposed to account for the formation of the 1,3-oxazolidines.
Cyclisation indolique selon Bischler en presence d'acides de Lewis
Galons, Herve,Girardeau, Jean-Francois,Farnoux, Claude Combet,Miocque, Marcel
, p. 561 - 564 (2007/10/02)
In a comparative study of various catalysts (hydrochloric acid, Lewis acids) in the Bischler cyclization of α-aminoketones to indoles, aluminium chloride appears as the most active catalyst.Isomerization of β to α-indoles can be observed by raising the reaction temperature.The mechanism seems different from the one frequently suggested by most authors, since it does not affect intermediate aminoketones but indoles.
