79349-24-9

Basic information

• Product Name: Phenol, 2-(3-phenyl-1,2,4-oxadiazol-5-yl)-
• CAS NO: 79349-24-9
• Molecular Formula: C14H10N2O2
• Molecular Weight: 238.246
• Mol File: 79349-24-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Phenol, 2-(3-phenyl-1,2,4-oxadiazol-5-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-(3-phenyl-1,2,4-oxadiazol-5-yl)-(79349-24-9)
• EPA Substance Registry System: Phenol, 2-(3-phenyl-1,2,4-oxadiazol-5-yl)-(79349-24-9)

Safety Data

• Hazardous Substances Data: 79349-24-9(Hazardous Substances Data)

Upstream product

• 873-67-6 benzonitrile oxide 
• 611-20-1 salicylonitrile 
• 1670-14-0 benzamidine monohydrochloride 
• 69-72-7 salicylic acid 
• 613-92-3 N-hydroxybenzenecarboximidamide 
• 100-47-0 benzonitrile 
• 613-92-3 N-hydroxyl-benzamidine 
• 347370-91-6 (1H-benzo[d][1,2,3]triazol-1-yl)(2-hydroxyphenyl)methanone 
• 1441-87-8 salicyloyl chloride 
• 932-90-1 Benzaldoxime 
• 134817-09-7 O-salicylbenzamidoxime 
• 90-02-8 salicylaldehyde 
• 55424-93-6 2-phenyl-4-oxo-1,3-benzoxazine perchlorate 

Downstream Products

• 245412-90-2 bis[5-(2-oxyphenyl)-3-phenyl-1,2,4-oxadiazolyl]copper(II) 
• 65004-23-1 5-(2-methoxyphenyl)-3-phenyl-1,2,4-oxadiazole 
• 134817-10-0 5-(2-acetoxyphenyl)-3-phenyl-1,2,4-oxadiazole 

Relevant articles and documents

Beyond direct Nrf2 activation; reinvestigating 1,2,4-oxadiazole scaffold as a master key unlocking the antioxidant cellular machinery for cancer therapy

Harnessing the antioxidant cellular machinery has sparked considerable interest as an efficient anticancer strategy. Activating Nrf2, the master switch of the cellular redox system, suppresses ROS, alleviates oxidative stress, and halts cancer progression

Synthesis of benzoxazines, quinazolines and 4H-benzo[e][1,3]thiazine by ANRORC rearrangements of 1,2,4-oxadiazoles

1,2,4-Oxadiazoles undergo ANRORC (addition of nucleophile, ring-opening and ring-closure) rearrangements upon reaction with excess of n-butyllithium to give benzoxazines, benzothiazines, and quinazolines in good yields under mild conditions. Georg Thieme Verlag Stuttgart · New York.

The role of the hydrogen bonding in cycloadditions of benzonitrile oxide with cyanophenols

The reactivity of aromatic nitriles in cycloadditions with benzonitrile oxide is remarkably enhanced by the ortho-hydroxy substituent. Semiempirical PM3 calculations are in agreement with a hydrogen bonding effect.