79388-11-7Relevant academic research and scientific papers
Synthesis of pyrido[1,2-a][1,3,5]triazine derivatives by aminomethylation of 6-amino-4-aryl-2-oxo-1,2-dihydropyridine-3,5-dicarbonitriles
Khrustaleva,Frolov,Dotsenko,Dmitrienko,Bushmarinov,Krivokolysko
, p. 46 - 52 (2014/05/06)
The aminomethylation of 6-amino-4-aryl-2-oxo-1,2-dihydropyridine-3,5- dicarbonitriles by treatment with primary amines and an excess of formaldehyde resulted in the formation of 3-R-8-aryl-6-oxo-1,3,4,6-tetrahydro-2H-pyrido[1,2- a][1,3,5]triazine-7,9-dica
A versatile synthesis, PM3-semiempirical, antibacterial, and antitumor evaluation of some bioactive pyrazoles
Hamama, Wafaa S.,El-Gohary, Hamada G.,Soliman, Mamdouh,Zoorob, Hanfi H.
body text, p. 543 - 554 (2012/08/27)
This research work describes the synthesis and biological properties of some novel isolated or fused heterocyclic ring systems with pyrazole, for example; enaminones containing pyrazolone ring photochromic functional unit, 4-[(4-chlorophenylamino)methylene]-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one (3) and some analogous derivatives 4, 9, and 10, also as pyrazolo[3,4-b]pyridine, pyrazolo[3,4-b]quinoline, pyrazolo[3',4':4,5]thieno[2,3-c]pyrazoline and pyrazolo[3,4-c]pyrazole were synthesized and characterized. Newly synthesized compounds were characterized by IR, 1H NMR, 13C NMR, mass spectral data and quantum mechanical calculations. Selected products were tested for their antibacterial and antitumor agents.
An efficient and greener approach to the synthesis of 3,5-dicyanopyridin- 2(1H)-one derivatives in aqueous media under microwave irradiation conditions
Jia, Runhong,Tu, Shujiang,Zhang, Yan,Jiang, Bo,Zhang, Junyong,Yao, Changsheng,Shi, Feng
, p. 1177 - 1180 (2008/04/12)
(Chemical Equation Presented) A facile and greener synthesis of a series of 3,5-dicyanopyridin-2(1H)-one derivatives was accomplished via the one-pot reaction of aldehyde, malononitrile and sodium hydroxide in aqueous media under microwave irradiation. Th
Nitriles in Heterocyclic Synthesis: The Reaction of 2-Thiocarbamoyl Cinnamonitriles with Active Methylene Reagents
El-Torgoman, Abdel Moneim,El-Kousy, Salah Mohamed,Kandeel, Zaghloul El-Shahat
, p. 107 - 112 (2007/10/02)
Substituted pyridin-2-thiones, 2-pyridones, thiopyranes and pyranoazoles could be synthesized via the reaction of 2-thiocarbamoyl cinnamonitriles with some active methylene reagents. - Key words: Heterocyclic Synthesis, 2-Thiocarbamoyl Cinnamonitriles
ON THE REACTION OF CYANOACETOHYDRAZIDE WITH α-SUBSTITUTED CINNAMONITRILES
Martin, Nazario,Seoane, Carlos,Soto, Jose L.
, p. 2013 - 2017 (2007/10/02)
The condensation of cyanoacetohydrazide with benzylidenemalononitriles is reinvestigated and a structure of 1,6-diamino-3,5-dicyano-2-pyridone is confirmed on the basis of chemical and spectroscopic evidence.
