794567-06-9Relevant academic research and scientific papers
Diastereo- and Enantioselective Synthesis of Bi- and Tricyclic N-Heterocycle-Fused β-Lactones
Kong, Weixu,Romo, Daniel
, p. 13161 - 13170 (2017/12/26)
The utility of the nucleophile-catalyzed (Lewis base) aldol lactonization (NCAL) process for the diastereo- and enantioselective synthesis of N-heterocycle-fused-β-lactones from N-linked ketoacids is described. A series of bi- and tricyclic, N-heterocycle
Organocatalytic synthesis of (2S,3R)-3-hydroxy-3-methyl-proline (OHMePro), a component of polyoxypeptins, and relatives using OHMePro itself as a catalyst
Yoshitomi, Yayoi,Makino, Kazuishi,Hamada, Yasumasa
, p. 2457 - 2460 (2008/02/05)
An efficient synthesis of (2S,3R)-3-hydroxy-3-methylproline (OHMePro), a component of polyoxypeptins, and relatives was achieved, in which an intramolecular asymmetric aldol reaction of the ketoaldehyde using OHMePro itself as an organocatalyst constitute
A short-step synthesis of (2S,3R)-3-hydroxy-3-methylproline, a component of polyoxypeptins, using a tandem Michael-aldol reaction and optical resolution
Makino, Kazuishi,Suzuki, Tatsuya,Hamada, Yasumasa
, p. 1649 - 1653 (2007/10/03)
A short-step synthesis of (2S,3R)-3-hydroxy-3-methylproline, a component of polyoxypeptins, using a tandem Michael-aldol reaction followed by its optical resolution using (-)-cinchonidine has been achieved.
