79611-55-5

Usage

Uses

Used in Pharmaceutical Industry:
3-(4-CHLOROPHENYL)-1,1,1-TRIFLUORO-2-PROPANONE is used as a starting material for the synthesis of various pharmaceutical compounds. Its unique chemical properties and high reactivity make it a valuable intermediate in the development of new drugs and medications.
Used in Agrochemical Industry:
In the agrochemical industry, 3-(4-CHLOROPHENYL)-1,1,1-TRIFLUORO-2-PROPANONE is utilized as a key component in the synthesis of agrochemicals. Its strong nucleophilic and electrophilic characteristics contribute to the development of effective pesticides and other agricultural chemicals.
Used in Research and Development:
3-(4-CHLOROPHENYL)-1,1,1-TRIFLUORO-2-PROPANONE is employed in research and development processes due to its unique chemical properties. It serves as a versatile intermediate for various chemical reactions, enabling scientists to explore new synthetic pathways and develop innovative compounds for various applications.

InChI:InChI=1/C9H6ClF3O/c10-7-3-1-6(2-4-7)5-8(14)9(11,12)13/h1-4H,5H2

Upstream product

• 383-63-1 ethyl trifluoroacetate, 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 874-72-6 4-chlorobenzylmagnesium chloride 
• 6332-83-8 2-(4-chlorophenyl)-1-phenylethanone 

Downstream Products

• 157735-88-1 3-(4-Chlorophenyl)-1,1,1-trifluorohex-5-en-2-one 
• 1148050-25-2 3-(4-chlorophenyl)-1,1,1-trifluoropropan-2-ol 
• 1602864-53-8 (3S,4R)-4-(4-bromophenyl)-3-(4-chlorophenyl)-1,1,1-trifluoro-5-nitropentan-2-one 
• 120428-45-7 2-amino-4-trifluoromethyl-5-(4-chlorophenyl)thiophene trifluoroacetic acid salt 
• 142154-88-9 4-(4-Chlorophenyl)-5-trifluoromethylpyrrole-3-carbonitrile 
• 171352-61-7 4-(4-chloro-phenyl)-5-trifluoromethyl-1H-pyrrole-2-carbonitrile 
• 157735-80-3 4-(4-chloro-phenyl)-5-trifluoromethyl-1H-pyrrole-2-carbaldehyde 
• 157735-89-2 3-(4-chloro-phenyl)-5,5,5-trifluoro-4-oxo-pentanal 
• 157735-81-4 3-(4-Chlorophenyl)-2-trifluoromethylpyrrole 
• 142154-87-8 3-(4-Chlorophenyl)-1,1,1-trifluoro-2-propanone oxime 

Relevant academic research and scientific papers

Highly efficient synthesis of chiral α-CF3 amines via Rh-catalyzed asymmetric hydrogenation

Highly enantioselective catalytic asymmetric hydrogenation of α-CF3-enamides has been achieved by employing rhodium-DuanPhos as the catalyst, which provides a readily accessible method for the synthesis of chiral trifluoromethylated amines. The reaction has a broad substrate scope; both aryl- and alkyl-substituted α-CF3-enamides worked smoothly and afford the corresponding chiral amines in high yields and excellent enantioselectivities (up to 99% ee).

Synthesis of trifluoromethyl ketones via tandem Claisen condensation and retro-Claisen C-C bond-cleavage reaction

A highly efficient, operationally simple approach to trifluoromethyl ketones has been developed that builds on the use of a tandem process involving Claisen condensation and retro-Claisen C-C bond cleavage reaction. Enolizable alkyl phenyl ketones were found to react readily with ethyl trifuoroacetate under the promotion of NaH to afford trifluoroacetic ester/ketone exchange products, trifluoromethyl ketones, which were quite different from the general Claisen condensation products, β-diketones. This procedure uses readily available starting materials and can be extended to the preparation of perfluoroalkyl ketones in excellent yield.

Synthesis of trifluoromethyl alcohols from tert-butoxy-β-(trifluoromethyl)styrenes and trifluoromethylbenzyl ketones under the conditions of the Leuckart-Wallach reaction

A novel pathway towards trifluoromethylalcohols by an unexpected reaction of tert-butoxy-β-(trifluoromethyl)styrenes or corresponding trifluoromethylbenzyl ketones under the conditions of the Leuckart-Wallach reaction was elaborated.

The Synthesis of Pyrroles with Insecticidal Activity

The 2-aryl-4-bromo-5-trifluoromethylpyrrole-3-carbonitriles represent a new class of insect control agents. The high insecticidal activity observed in this series prompted us to investigate the preparation of regioisomeric arylhalotrifluoromethylpyrrole c

Bis- and tris(trifluoromethyl)arylpyrrole insecticidal and acaricidal agents

Bis- and tris(trifluoromethyl)arylpyrrole compounds which are effective for the control of insects and acarids are described. A method for the insecticidal and acaricidal use of said compounds and methods for the preparation of said compounds are presente

Process for the preparation of insecticidal, nematicidal and acaricidal 4-substituted-5-(trifluoromethyl)pyrrole-3-carbonitrile compounds

There is provided a process for the preparation of 4-substituted-5-(trifluoromethyl)pyrrole-3-carbonitrile compounds which are useful as insecticidal, nematicidal and acaricidal agents.