79615-75-1

Basic information

• Product Name: 1-(4-(neopentyloxy)phenyl)ethan-1-one
• Synonyms: 1-(4-(neopentyloxy)phenyl)ethan-1-one
• CAS NO: 79615-75-1
• Molecular Weight: 206.285
• Mol File: 79615-75-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(4-(neopentyloxy)phenyl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(neopentyloxy)phenyl)ethan-1-one(79615-75-1)
• EPA Substance Registry System: 1-(4-(neopentyloxy)phenyl)ethan-1-one(79615-75-1)

Safety Data

• Hazardous Substances Data: 79615-75-1(Hazardous Substances Data)

Upstream product

• 75-84-3 2,2-dimethyl-propanol-1 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 99-90-1 para-bromoacetophenone 
• 630-17-1 2,2-dimethylpropyl bromide 
• 99-93-4 4-Hydroxyacetophenone 
• 623-03-0 4-Cyanochlorobenzene 
• 917-64-6 methyl magnesium iodide 
• 79615-68-2 4-(neopentyloxy)benzonitrile 

Downstream Products

• 79615-90-0 2-Chloro-1-[4-(2,2-dimethyl-propoxy)-phenyl]-ethanone 
• 1574394-73-2 C₁₆H₂₂O₄ 
• 1574394-57-2 C₁₅H₁₉N₃O₂ 
• 79615-46-6 4-[4-(2,2-Dimethyl-propoxy)-phenyl]-thiazol-2-ylamine; hydrochloride 

Relevant articles and documents

Phosphazene Base tBu-P4 Catalyzed Methoxy–Alkoxy Exchange Reaction on (Hetero)Arenes

The organic superbase tBu-P4 catalyzes methoxy-alkoxy exchange reactions on (hetero)arenes with alcohols. The catalytic reaction proceeded efficiently with electron-deficient methoxy(hetero)arenes as well as with a variety of alcohols, including 3-amino-1-propanol, β-citronellol, menthol, and cholesterol. An intramolecular version of this reaction furnished six- and seven-membered ring compounds.

Switching on elusive organometallic mechanisms with photoredox catalysis

Transition-metal-catalysed cross-coupling reactions have become one of the most used carbon-carbon and carbon-heteroatom bond-forming reactions in chemical synthesis. Recently, nickel catalysis has been shown to participate in a wide variety of C-C bond-forming reactions, most notably Negishi, Suzuki-Miyaura, Stille, Kumada and Hiyama couplings. Despite the tremendous advances in C-C fragment couplings, the ability to forge C-O bonds in a general fashion via nickel catalysis has been largely unsuccessful. The challenge for nickel-mediated alcohol couplings has been the mechanistic requirement for the critical C-O bond-forming step (formally known as the reductive elimination step) to occur via a Ni(iii) alkoxide intermediate. Here we demonstrate that visible-light-excited photoredox catalysts can modulate the preferred oxidation states of nickel alkoxides in an operative catalytic cycle, thereby providing transient access to Ni(iii) species that readily participate in reductive elimination. Using this synergistic merger of photoredox and nickel catalysis, we have developed a highly efficient and general carbon-oxygen coupling reaction using abundant alcohols and aryl bromides. More notably, we have developed a general strategy to 'switch on' important yet elusive organometallic mechanisms via oxidation state modulations using only weak light and single-electron-transfer catalysts.

2-Amino-4-phenylthiazole derivatives as anti-atherogenic agents

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