79618-02-3

Upstream product

• 77877-19-1 N-isopropyl oxazolidinone 
• 100-52-7 benzaldehyde 
• 186355-83-9 (2'RS,4S)-3-(2'-bromopropanoyl)-4-(1-methylethyl)-oxazolidin-2-one 

Downstream Products

• 76549-03-6 methyl (2S,3S)-3-hydroxy-2-methyl-3-phenylpropanoate 
• 76549-05-8 methyl (2R,3R)-3-hydroxy-2-methyl-3-phenylpropanoate 
• 36041-80-2 (2R,3S)-methyl 3-hydroxy-2-methyl-3-phenylpropanoate 

Relevant academic research and scientific papers

Synthesis of γ-Lactones via the kowalski homologation reaction: Protecting-group-free divergent total syntheses of eupomatilones-2,5,6, and 3- epi-eupomatilone-6

A highly efficient synthesis of functionalized chiral γ-butyrolactone scaffolds has been described. The basis of the approach is the Kowalski ester homologation that is modified for our proposed transformation. The newly developed methodology combines a d

HIGHLY STEREOSELECTIVE REFORMATSKY REACTIONS OF 3-(2-BROMOPROPIONYL)-2-OXAZOLIDONE DERIVATIVES WITH VARIOUS ALDEHYDES

The Reformatsky reactions of 3-(2-bromopropionyl)-2-oxazolidone derivatives with various aldehydes were investigated to elucidate the effects of substituents in the 2-oxazolidone moieties on their diastereoselectivities.The highest 2,3-syn-diastereoselect