796729-03-8

Basic information

• Product Name: INDEX NAME NOT YET ASSIGNED
• Synonyms: 4H,5H,6H-pyrrolo[1,2-b]pyrazole-2-carboxylic acid;4H-Pyrrolo[1,2-b]pyrazole-2-carboxylic acid, 5,6-dihydro-
• CAS NO: 796729-03-8
• Molecular Formula: C₇H₈N₂O₂
• Molecular Weight: 152.152
• Product Categories: METHYL
• Mol File: 796729-03-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 381.6 °C at 760 mmHg
• Flash Point: 184.6 °C
• Appearance: /
• Density: 1.55
• Storage Temp.: 2-8°C
• PKA: 4.12±0.20(Predicted)
• CAS DataBase Reference: INDEX NAME NOT YET ASSIGNED(CAS DataBase Reference)
• NIST Chemistry Reference: INDEX NAME NOT YET ASSIGNED(796729-03-8)
• EPA Substance Registry System: INDEX NAME NOT YET ASSIGNED(796729-03-8)

Safety Data

• Hazardous Substances Data: 796729-03-8(Hazardous Substances Data)

Usage

General Description

The chemical "INDEX NAME NOT YET ASSIGNED" is a compound that is currently under investigation and has not yet been assigned an official name. It is likely to be a new or emerging substance that requires further testing and analysis to determine its properties, uses, and potential risks. Until it is officially named and classified, there is limited information available about this chemical, and caution should be exercised when handling or using it. Research and regulatory agencies are working to gather more data on "INDEX NAME NOT YET ASSIGNED" to ensure its safe and proper management in the future.

Upstream product

• 1454848-65-7 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylic acid methyl ester 
• 98262-66-9 3a,4,5,6-tetrahydro-3-oxo-3H-pyrrolo[1,2-c][1,2,3]oxadiazol-7-ium ylide 
• 623-47-2 propynoic acid ethyl ester 
• 86477-10-3 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carboxylic acid ethyl ester 
• 86477-09-0 ethyl 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylate 

Downstream Products

• 459157-32-5 3-nitro-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylic acid 
• 1454848-65-7 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carboxylic acid methyl ester 

Relevant articles and documents

Focal adhesion kinase inhibitor and use

The invention belongs to the field of medicines, relates to a focal adhesion kinase inhibitor and use, in particular relates to a novel focal adhesion kinase inhibitor compound, or stereoisomers, geometric isomers, tautomers, oxynitrides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or prodrugs thereof, further relates to the use of the compound and pharmaceutical compositions as medicines, in particular the use of the compound and pharmaceutical compositions in manufacture of medicines for treatment or prevention of cancer, pulmonary hypertension, and pathological angiogenesis-related diseases.

8-FLUOROPHTHALAZIN-1(2H)-ONE COMPOUNDS

8-Fluorophthalazin-1(2h)-one compounds of Formula II where one or two of X1, X2, and X3 are N, are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula II for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Selective hydrolysis of ethyl 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2- carboxylate and ethyl 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carboxylate as a key step in the large-scale synthesis of bicyclic heteroaryl carboxyaldehydes

The isomeric mixture of ethyl 5,6-dihydro-4H-pyrrolo[1,2-b]-pyrazole-2- and -3-carboxylates (14 and 15), derived from a proline meso-ionic synthon, demonstrated remarkably different stabilities towards alkaline hydrolysis. On that basis, a non-chromatographic, highly efficient method for their large-scale separation was developed. The desired isomer 14 was converted into 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-2-carbaldehyde, a key intermediate in the synthesis of bicyclic heteroaryl-substituted 6-alkylidene penems.