79839-66-0

Basic information

• Product Name: 2-Bromo-N,N-diisopropylbenzamide
• Synonyms: 2-Bromo-N,N-diisopropylbenzamide;N-Diisopropyl 2-bromobenzamide
• CAS NO: 79839-66-0
• Molecular Formula: C₁₃H₁₈BrNO
• Molecular Weight: 284.19
• Product Categories: blocks;Bromides;Carboxes
• Mol File: 79839-66-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Bromo-N,N-diisopropylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-N,N-diisopropylbenzamide(79839-66-0)
• EPA Substance Registry System: 2-Bromo-N,N-diisopropylbenzamide(79839-66-0)

Safety Data

• Hazardous Substances Data: 79839-66-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-N,N-diisopropylbenzamide is used as a key intermediate for the synthesis of various pharmaceuticals, specifically for the production of antihypertensive and anti-inflammatory drugs. Its chemical structure allows for the development of medications that can effectively manage blood pressure and reduce inflammation.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Bromo-N,N-diisopropylbenzamide is utilized as a precursor in the formulation of herbicides and insecticides. Its incorporation aids in the creation of products that protect crops from pests and unwanted plant species, thereby ensuring increased agricultural productivity.
Safety Precautions:
It is imperative to handle 2-Bromo-N,N-diisopropylbenzamide with care due to its potential to cause skin and eye irritation. To mitigate such risks, it should be used in well-ventilated areas, and individuals working with BDI must employ appropriate protective equipment.

Upstream product

• 20383-28-2 N,N-diisopropyl benzamide 
• 108-18-9 diisopropylamine 
• 88-65-3 2-bromobenzoic-acid 
• 98-88-4 benzoyl chloride 
• 7154-66-7 2-bromobenzoic acid chloride 

Downstream Products

• 132464-44-9 N,N-diisopropyl-2-(naphthalen-1-yl)benzamide 
• 1616609-94-9 2-(benzo[d][1,3]dioxol-5-yl)-N,N-diisopropylbenzamide 
• 6630-33-7 ortho-bromobenzaldehyde 
• 815581-73-8 2-borylated-N,N-diisopropylbenzamide 
• 207802-72-0 N,N-diisopropyl-2-[3-methoxy(N-methyl)anilino]benzamide 
• 62924-99-6 2-deuterio-N,N-diisopropylbenzamide 
• 88-65-3 2-bromobenzoic-acid 
• 207802-66-2 N,N-diisopropyl-2-(3-methoxyanilino)benzamide 

Relevant articles and documents

Identification of key functionalization species in the Cp?Ir(iii)-catalyzed-: ortho halogenation of benzamides

Cp?Ir(iii) complexes have been shown to be effective for the halogenation of N,N-diisopropylbenzamides with N-halosuccinimide as a suitable halogen source. The optimized conditions for the iodination reaction consist of 0.5 mol% [Cp?IrCl2]2 in 1,2-dichlor

Directed: Ortho-metalation-nucleophilic acyl substitution strategies in deep eutectic solvents: The organolithium base dictates the chemoselectivity

Directed ortho metalation (DoM) or nucleophilic acyl substitution (SNAc) can be efficiently programmed on the same aromatic carboxylic acid amide, in a choline chloride-based eutectic mixture, by simply switching the nature of the organolithium reagent. Telescoped, one-pot ortho-lithiation/Suzuki-Miyaura cross-couplings have also been demonstrated for the first time in Deep Eutectic Solvents.

Amide Effects in C?H Activation: Noncovalent Interactions with L-Shaped Ligand for meta Borylation of Aromatic Amides

A new concept for the meta-selective borylation of aromatic amides is described. It has been demonstrated that while esters gave para borylations, amides lead to meta borylations. For achieving high meta selectivity, an L-shaped bifunctional ligand has been employed and engages in an O???K noncovalent interaction with the oxygen atom of the moderately distorted amide carbonyl group. This interaction provides exceptional control for meta C?H activation/borylation.

Ruthenium-catalyzed ortho-C-H halogenations of benzamides

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Employing a robustness screen: Rapid assessment of rhodium(III)-catalysed C-H activation reactions This paper is dedicated to Professor Paul A. Wender, a great scientist, teacher and mentor

Following the discovery of new synthetic methodology, an assessment of its potential utility in real synthetic problems is highly desirable to facilitate its application. Herein, we describe an assessment of two contemporary rhodium catalysed C-H activati

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The development of the intramolecular arylation of sp3 C-H bonds adjacent to nitrogen using aryl halides is described. Arylation was accomplished using either Ni(COD)2 or 1,10-phenanthroline in substoichiometric amounts, and the reaction conditions were applied to a variety of electronically differentiated benzamide substrates. Preliminary studies suggest a mechanism involving aryl and alkyl radical intermediates.

High-yielding, versatile, and practical [Rh(III)Cp*]-catalyzed ortho bromination and iodination of arenes

We report a uniquely high-yielding, general, and practical ortho bromination and iodination reaction of different classes of aromatic compounds. This reaction occurs by Rh(III)-catalyzed C-H bond activation methodology and is therefore the first example of the application of this cationic catalyst for C-Br and C-I bond formation.

BENZOFLUORENE COMPOUND AND USE THEREOF

A novel material having high hole-transporting ability and a high glass transition temperature and having long-lasting durability is obtained. A benzofluorene compound represented by formula (1) is used. (In the formula, M is a substituted or unsubstituted aryl group having 6-40 carbon atoms or a substituted or unsubstituted heteroaryl group having 5-40 carbon atoms; Ar1 to Ar4 each independently is a substituted or unsubstituted aryl group having 6-40 carbon atoms or a substituted or unsubstituted heteroaryl group having 5-40 carbon atoms, provided that at least one of Ar1 to Ar4 is a substituent represented by any of the following formulae (2) to (5); and p is an integer of 0-2.) (In the formulae, R1 to R4 each independently is a hydrogen atom, a halogen atom, a substituted or unsubstituted amino group, a linear, branched, or cyclic alkyl group, a linear, branched, or cyclic alkoxy group, a substituted or unsubstituted aryl group having 6-40 carbon atoms, or a substituted or unsubstituted aryloxy group having 6-40 carbon atoms, provided that R1 and R2 may be bonded to each other to form a ring.)

Carbanionic friedel-crafts equivalents. Regioselective directed Ortho and remote metalation-C-N cross coupling routes to acridones and dibenzo[b,f]azepinones

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