79839-66-0

Basic information

• Product Name: 2-Bromo-N,N-diisopropylbenzamide
• Synonyms: 2-Bromo-N,N-diisopropylbenzamide;N-Diisopropyl 2-bromobenzamide
• CAS NO: 79839-66-0
• Molecular Formula: C₁₃H₁₈BrNO
• Molecular Weight: 284.19
• Product Categories: blocks;Bromides;Carboxes
• Mol File: 79839-66-0.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Bromo-N,N-diisopropylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-N,N-diisopropylbenzamide(79839-66-0)
• EPA Substance Registry System: 2-Bromo-N,N-diisopropylbenzamide(79839-66-0)

Safety Data

• Hazardous Substances Data: 79839-66-0(Hazardous Substances Data)

Usage

General Description

2-Bromo-N,N-diisopropylbenzamide, also known as BDI, is a chemical compound used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is a white to off-white crystalline powder with a molecular formula of C15H22BrNO and a molecular weight of 312.25 g/mol. BDI is commonly employed as a building block in the production of antihypertensive and anti-inflammatory drugs, as well as herbicides and insecticides. It is important to handle BDI with caution as it can cause skin and eye irritation, and should be used in a well-ventilated area with appropriate protective equipment.

Upstream product

• 7154-66-7 2-bromobenzoic acid chloride 
• 108-18-9 diisopropylamine 
• 98-88-4 benzoyl chloride 
• 88-65-3 2-bromobenzoic-acid 
• 20383-28-2 N,N-diisopropyl benzamide 

Downstream Products

• 207802-66-2 N,N-diisopropyl-2-(3-methoxyanilino)benzamide 
• 88-65-3 2-bromobenzoic-acid 
• 62924-99-6 2-deuterio-N,N-diisopropylbenzamide 
• 132464-44-9 N,N-diisopropyl-2-(naphthalen-1-yl)benzamide 
• 1616609-94-9 2-(benzo[d][1,3]dioxol-5-yl)-N,N-diisopropylbenzamide 
• 815581-73-8 2-borylated-N,N-diisopropylbenzamide 
• 6630-33-7 ortho-bromobenzaldehyde 
• 207802-72-0 N,N-diisopropyl-2-[3-methoxy(N-methyl)anilino]benzamide 

Relevant articles and documents

Identification of key functionalization species in the Cp?Ir(iii)-catalyzed-: ortho halogenation of benzamides

Cp?Ir(iii) complexes have been shown to be effective for the halogenation of N,N-diisopropylbenzamides with N-halosuccinimide as a suitable halogen source. The optimized conditions for the iodination reaction consist of 0.5 mol% [Cp?IrCl2]2 in 1,2-dichlor

Amide Effects in C?H Activation: Noncovalent Interactions with L-Shaped Ligand for meta Borylation of Aromatic Amides

A new concept for the meta-selective borylation of aromatic amides is described. It has been demonstrated that while esters gave para borylations, amides lead to meta borylations. For achieving high meta selectivity, an L-shaped bifunctional ligand has been employed and engages in an O???K noncovalent interaction with the oxygen atom of the moderately distorted amide carbonyl group. This interaction provides exceptional control for meta C?H activation/borylation.

Ruthenium-catalyzed ortho-C-H halogenations of benzamides

[Ru3(CO)12] and AgO2C(1-Ad) enabled the first ruthenium-catalyzed intermolecular halogenations of arenes via C-H activation. Thereby, brominations and iodinations of electron-rich and electron-deficient benzamides were ach