79866-42-5

Upstream product

• 78146-52-8 phenylglyoxal monohydrate 
• 106-40-1 4-bromo-aniline 
• 67-56-1 methanol 
• 1075-06-5 2,2-dihydroxy-1-phenyl-ethanone 
• 4831-21-4 2-((4-bromophenyl)amino)-1-phenylethan-1-one 

Downstream Products

• 109685-29-2 4-Benzoyl-1-(p-bromophenyl)-3,3-dimethyl-2-azetidinone 
• 109685-25-8 Methyl 3-(p-bromophenyl)amino-2,2-dimethyl-4-oxo-4-phenylbutanoate 
• 131856-83-2 Methyl 4-(p-bromophenyl)imino-3-hydroxy-2,2-dimethyl-3-phenylbutanoate 
• 109685-18-9 4-(4-Bromo-phenylamino)-3-hydroxy-4-methoxy-2,2-dimethyl-3-phenyl-butyric acid methyl ester 
• 131856-96-7 Methyl (2S^*,3R^*)-4-(p-bromophenyl)imino-3-hydroxy-2-methyl-3-phenylbutanoate 
• 131856-96-7 Methyl (2R^*,3R^*)-4-(p-bromophenyl)imino-3-hydroxy-2-methyl-3-phenylbutanoate 
• 131856-85-4 Methyl 1-<2'-(N-p-bromophenyl)imino-1'-hydroxy-1'-phenylethyl>cyclohexanecarboxylate 
• 131857-20-0 3-Benzoyl-2-(p-bromophenyl)-1-oxo-2-azaspiro<3.5>nonane 
• 131856-91-2 Methyl 4-(p-bromophenyl)imino-3-hydroxy-3-phenylbutanoate 
• 131857-12-0 Methyl 3-(p-bromophenyl)amino-4-oxo-4-phenylbutanoate 
• 91851-17-1 2-((4-bromophenyl)amino)-1-phenylethan-1-ol 

Relevant academic research and scientific papers

REGIOCONTROLLED ADDITION IN THE REACTION OF N-(α-METHOXYPHENACYL)ANILINES WITH METHYL LITHIOISOBUTYRATE

Reaction of various para-substituted N-(α-methoxyphenacyl)anilines with lithioisobutyrate in excess gives, in good yield, compounds 2-6 through a regiocontrolled process.

The Reaction of Phenylglyoxal with Primary Aliphatic and Aromatic Amines. Synthesis of Phenylglyoxal Monoimines and some Derivatives.

Condensation of phenylglyoxal with primary aliphatic amines yields the related keto-aldimines.When primary aromatic amines are used, aldimines, amino-hydroxy-ketones, diamino-ketones, and alkoxy-amino-ketones are obtained depending upon the nature of the amine and the experimental conditions.Alternatively the monoimines can be obtained by dehydration of C-hydroxyphenacylarylamines and by demethanolation of C-methoxyphenacylarylamines both on treatment with Pd/C catalyst.Reduction of phenylglyoxal monoimines with sodium borohydride yielded H-substituted 1-phenyl-2-aminoethanols and 1,3-dipolar cycloaddition of the imines with p-chlorobenzonitrile oxide afforded 4-substituted 5-benzoyl-3-(p-chlorophenyl)-4,5-dihydro-1,2,4-oxadiazoles.

Removal of Toluene-p-sulphonyl Groups from Sulphonamides. Part 4. Synthesis of Phenylglyoxal Imine Monomers

Syntheses and reactions of N-tosylphenacylamines with bases have been systematically examined.Monomeric C-methoxy-imines are available from some of these reactions.C-Methoxyphenacylarylamines, made by two routes, were converted into monomeric imines on treatment with noble-metal catalysts, The boron trifluoride-catalysed reactions of aryl aldehydes with sulphonamides provide a new and convenient route to N-sulphonylarylimines.