80-38-6

Basic information

• Product Name: FENSON
• Synonyms: (4-Chloor-fenyl)-benzeen-sulfonaat;(4-chloor-fenyl)-benzeen-sulfonaat[qr];(4-Chlor-phenyl)-benzolsulfonat;(4-chlor-phenyl)-benzolsulfonat[qr];(4-Cloro-fenil)-benzol-solfonato;(4-cloro-fenil)-benzol-solfonato[qr];4-chlorophenyl;4-Chlorophenyl benzenesulphonate
• CAS NO: 80-38-6
• Molecular Formula: C₁₂H₉ClO₃S
• Molecular Weight: 268.72
• EINECS: 201-274-6
• Mol File: 80-38-6.mol
• Article Data: 13

Chemical Properties

• Melting Point: 62℃
• Boiling Point: 407.0±37.0 °C(Predicted)
• Flash Point: >100 °C
• Appearance: /
• Density: 1.33 g/cm3
• Storage Temp.: 0-6°C
• BRN: 2696927
• CAS DataBase Reference: FENSON(CAS DataBase Reference)
• NIST Chemistry Reference: FENSON(80-38-6)
• EPA Substance Registry System: FENSON(80-38-6)

Safety Data

• Hazard Codes: Xn,N
• Statements: 22-36-51/53
• Safety Statements: 24-26-61
• RIDADR: UN3077 9/PG 3
• WGK Germany: 2
• RTECS: DB5600000
• Hazardous Substances Data: 80-38-6(Hazardous Substances Data)

Usage

Chemical Properties

Colorless crystals. Soluble in organic solvents; insoluble in water.

InChI:InChI=1/C12H9ClO3S/c13-10-6-8-11(9-7-10)16-17(14,15)12-4-2-1-3-5-12/h1-9H

Upstream product

• 106-48-9 4-chloro-phenol 
• 98-09-9 benzenesulfonyl chloride 
• 126644-72-2 1-<(tert-butyldimethylsilyl)oxy>-4-chlorobenzene 
• 133745-75-2 N-fluorobis(benzenesulfon)imide 
• 873-55-2 sodium benzenesulfonate 
• 3313-84-6 4-nitrophenyl benzenesulfonate 
• 14915-23-2 p-Chlorophenol-OD 
• 2297-65-6 benzenesulfonyl bromide 
• 4106-18-7 1-(phenylsulfonyl)-1H-benzo[d][1,2,3]triazole 
• 4358-63-8 phenyl benzenesulfonate 

Downstream Products

• 2948-37-0 N-(4-chlorophenyl)benzylamine 
• 837-18-3 N-benzylbenzenesulfonamide 
• 106-48-9 4-chloro-phenol 
• 98-11-3 benzenesulfonic acid 
• 839-51-0 N-(4-methylbenzyl)-4-methybenzenesulfonamide 
• 73842-46-3 N-[(4-methylphenyl)methyl]-4-chloroaniline 
• 16212-06-9 phenyl styryl sulfone 
• 288264-09-5 2-benzenesulfonyl-4-chloro-phenol 
• 104329-18-2 N-(4-chlorophenyl)-4-methoxybenzenemethanamine 
• 79246-03-0 N-(4-methoxybenzyl)-4-methybenzenesulfonamide 
• 13159-74-5 4-chloro-N-(4-chlorobenzyl)aniline 
• 10504-97-9 N-(2-chlorobenzyl)-4-methybenzenesulfonamide 

Relevant articles and documents

Practical Electro-Oxidative Sulfonylation of Phenols with Sodium Arenesulfinates Generating Arylsulfonate Esters

A practical and sustainable synthesis of arylsulfonate esters has been developed through electro-oxidation. This reaction employed the stable and readily available phenols and sodium arenesulfinates as the starting materials and took place under mild reaction conditions without additional oxidants. A wide range of arylsulfonate esters including those bearing functional groups were produced in good to excellent yields. This reaction could also be conducted at a gram scale without a decrease of reaction efficiency. Those results well demonstrated the potential synthetic value of this reaction in organic synthesis.

NFSI/KF mediated mild and chemoselective interconversion of aryl TBDMS ethers to their benzene sulfonate

A one pot protocol for the transformation of aryl TBDMS ethers to corresponding benzene sulfonate esters using NFSI (N-flurobenzenesulfonimide)/KF is described. In situ generation of benzenesulfonyl fluoride directs chemoselective cleavage of aryl silyl ethers over alkyl silyl ethers. Electron withdrawing substituent's on aryl ring provided better yield than donating groups. Protecting groups and sensitive functionalities are well tolerated in this methodology. Thus, commercially available inexpensive reagents, mild reaction conditions and step economy are the advantages of this method.

Iodine-induced synthesis of sulfonate esters from sodium sulfinates and phenols under mild conditions

An iodine-induced synthesis of sulfonate esters via cross-coupling reactions of sodium sulfinates with phenols is reported. This synthetic route is low-cost, facile, green and efficient, and could afford the target products with good to excellent yields u