80015-58-3Relevant academic research and scientific papers
CYCLIC DINUCLEOTIDES AS STING AGONISTS
-
, (2020/02/14)
Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I), wherein R1, R1', X1, B1
Towards the preparation of 2″-deoxy-2″-fluoro-adenophostin A. Study of the glycosylation reaction
Benito, David,Matheu, M. Isabel,Morère, Alain,Díaz, Yolanda,Castillón, Sergio
, p. 10906 - 10911 (2008/12/23)
The synthesis of 2″-deoxy-2″-fluoro-adenophostin A framework starting from tri-O-acetylglucal and adenosine is described. The key steps are the formation of the 2-deoxy-2-fluoroglycosyl donor by electrophilic fluorination of tri-O-acetylglucal and the ste
SYNTHESIS OF 2'- OR 3'-O-(4-METHOXYBENZYL)NUCLEOSIDES AND ITS APPLICATION IN THE 3'-TERMINAL NONANUCLEOTIDE SEQUENCE OF ROUS SARCOMA VIRUS 35S RNA SYNTHESIS
Kamaike, Kazuo,Tsuchiya, Hiromichi,Imai, Kazuaki,Takaku, Hiroshi
, p. 4701 - 4712 (2007/10/02)
2'- or 3'-O-(4-Methoxybenzyl)nucleoside derivatives were synthesized by treatment of uridine, N4-benzoylcytidine, N6-benzoyladenosine, and N2-benzoylguanosine with 4-methoxyphenyldiazomethane.The separation of 2'- or 3'- i
SYNTHESIS OF OLIGORIBONUCLEOTIDES USING 4-METHOXYBENZYL GROUP AS A NEW PROTECTING GROUP OF THE 2'-HYDROXYL GROUP OF ADENOSINE
Takaku, Hiroshi,Kamaike, Kazuo
, p. 189 - 192 (2007/10/02)
4-Methoxybenzyl group was introduced directlyto the 2'-hydroxyl group from the reaction of adenosine with 4-methoxybenzyl bromide in the presence of sodium hydride.The 2'-O-(4-methoxybenzyl)-adenosine can be successfully used in the synthesis of oligoribo
