80015-60-7

Upstream product

• 98-88-4 benzoyl chloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 824-94-2 p-methoxybenzyl chloride 
• 5953-85-5 (4-methoxybenzylidene)-hydrazine 
• 23304-25-8 p-methoxyphenyldiazomethane 
• 58-61-7 adenosine 
• 80015-54-9 (2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)- 2-(hydroxymethyl)-4-((4-methoxybenzyl)oxy)tetrahydrofuran-3-ol 
• 2746-25-0 p-Methoxybenzyl bromide 

Downstream Products

• 109049-53-8 Phosphoric acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(4-methoxy-benzyloxy)-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 5-chloro-quinolin-8-yl ester 
• 478050-92-9 N⁶-benzoyl-5'-O-dimethoxytrityl-2'-O-(4-methoxybenzyl)-3'-[[bis(benzyloxy)phosphoryl]oxy]adenosine 
• 478050-94-1 N⁶-benzoyl-5'-O-[bis(allyloxy)phosphoryl]-3'-O-[bis(benzyloxy)phosphoryl]-2'-O-(4-methoxybenzyl)adenosine 
• 478050-95-2 5'-O-[bis(allyloxy)phosphoryl]-3'-O-[bis(benzyloxy)phosphoryl]-2'-O-(4-methoxybenzyl)adenosine 
• 478050-93-0 N⁶-benzoyl-3'-O-[bis(benzyloxy)phosphoryl]-2'-O-(4-methoxybenzyl)adenosine 
• 478050-91-8 3'-O-[bis(benzyloxy)phosphoryl]-2'-O-(4-methoxybenzyl)-5'-O-phosphate adenosine 

Relevant academic research and scientific papers

CYCLIC DINUCLEOTIDES AS STING AGONISTS

Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I), wherein R1, R1', X1, B1

SYNTHESIS OF 2'- OR 3'-O-(4-METHOXYBENZYL)NUCLEOSIDES AND ITS APPLICATION IN THE 3'-TERMINAL NONANUCLEOTIDE SEQUENCE OF ROUS SARCOMA VIRUS 35S RNA SYNTHESIS

2'- or 3'-O-(4-Methoxybenzyl)nucleoside derivatives were synthesized by treatment of uridine, N4-benzoylcytidine, N6-benzoyladenosine, and N2-benzoylguanosine with 4-methoxyphenyldiazomethane.The separation of 2'- or 3'- i

SYNTHESIS OF OLIGORIBONUCLEOTIDES USING 4-METHOXYBENZYL GROUP AS A NEW PROTECTING GROUP OF THE 2'-HYDROXYL GROUP OF ADENOSINE

4-Methoxybenzyl group was introduced directlyto the 2'-hydroxyl group from the reaction of adenosine with 4-methoxybenzyl bromide in the presence of sodium hydride.The 2'-O-(4-methoxybenzyl)-adenosine can be successfully used in the synthesis of oligoribo