80077-71-0

Basic information

• Product Name: diethyl (1,1-difluorobut-3-en-1-yl)phosphonate
• Synonyms: diethyl (1,1-difluorobut-3-en-1-yl)phosphonate
• CAS NO: 80077-71-0
• Molecular Weight: 228.176
• Mol File: 80077-71-0.mol

Chemical Properties

• CAS DataBase Reference: diethyl (1,1-difluorobut-3-en-1-yl)phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl (1,1-difluorobut-3-en-1-yl)phosphonate(80077-71-0)
• EPA Substance Registry System: diethyl (1,1-difluorobut-3-en-1-yl)phosphonate(80077-71-0)

Safety Data

• Hazardous Substances Data: 80077-71-0(Hazardous Substances Data)

Upstream product

• 80084-30-6 (diethylphosphono)difluoromethyl cadmium bromide 
• 106-95-6 allyl bromide 
• 556-56-9 allyl iodid 
• 65094-22-6 diethyl (bromodifluoromethyl)phosphonate 
• 107-05-1 3-chloroprop-1-ene 

Downstream Products

• 214205-17-1 [6-(2,4-difluoro-5-methyl-phenyl)-3-ethoxythiocarbonylsulfanyl-1,1-difluoro-6-oxo-hexyl]-phosphonic acid diethyl ester 
• 214205-18-2 {2-[5-(2,4-difluoro-5-methyl-phenyl)-2,3-dihydro-thiophen-2-yl]-1,1-difluoro-ethyl}-phosphonic acid diethyl ester 

Relevant articles and documents

Addition of Diethyl Bromodifluoromethylphosphonate to Various Alkenes Initiated by Co(III)/Zn Bimetal Redox System

The addition of diethyl bromodifluoromethylphosphonate 1 to various alkenes 2 initiated by cobaloxime(III)/Zn bimetal redox system gives 1:1 Michael-type adducts 3 in moderate to good yields.A radical mechanism is proposed.

FLUORINE IN ENZYME CHEMISTRY: PART 1. SYNTHESIS OF DIFLUOROMETHYLENEPHOSPHONATE DERIVATIVES AS PHOSPHATE MIMICS

Diethyl difluoromethylphosphonylcadmium bromide reacts with allyl and benzyl halides in THF to give the corresponding difluoromethylenephosphonate derivatives.The reaction with allyl bromide affords a versatile synthetic intermediate which undergoes a variety of synthetic transformations and therefore becomes a key compound in the preparation of elaborated difluoromethylenephosphonates of biological significance.