80110-73-2

Basic information

• Product Name: 2,6-DiMethyltyrosine HCl
• Synonyms: 2,6-DiMethyltyrosine HCl;L-2,6-DiMethyltyrosine HCl
• CAS NO: 80110-73-2
• Molecular Formula: C11H16ClNO3
• Molecular Weight: 245.70264
• Mol File: 80110-73-2.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,6-DiMethyltyrosine HCl(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DiMethyltyrosine HCl(80110-73-2)
• EPA Substance Registry System: 2,6-DiMethyltyrosine HCl(80110-73-2)

Safety Data

• Hazardous Substances Data: 80110-73-2(Hazardous Substances Data)

Usage

General Description

2,6-DiMethyltyrosine HCl is a chemical compound that is primarily used in pharmaceutical and research applications. It is a derivative of the amino acid tyrosine, with two methyl groups attached to the 2 and 6 positions of the aromatic ring. The HCl salt form of the compound enhances its solubility in water, making it easier to handle and use in various experimental settings. 2,6-DiMethyltyrosine HCl is known for its potential to act as a precursor in the synthesis of various natural and pharmacologically active compounds. Additionally, it has shown promise in studies related to Parkinson's disease and other neurological disorders, as well as in the development of new drugs targeting specific protein receptors. Overall, 2,6-DiMethyltyrosine HCl is a versatile chemical with a wide range of potential applications.

Upstream product

• 928138-99-2 (R)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionic acid methyl ester; hydrochloride 
• 928138-99-2 (S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionic acid methyl ester; hydrochloride 
• 81806-45-3 2',6'-dimethyltyrosine 
• 99953-00-1 (S)-N-Boc-2,6-dimethyltyrosine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 28924-92-7 4-(benzyloxy)-2,6-dimethylbenzaldehyde 
• 70547-87-4 2,6-dimethyl-4-hydroxybenzaldehyde 

Relevant articles and documents

Preparation of Constrained Unnatural Aromatic Amino Acids via Unsaturated Diketopiperazine Intermediate

Unnatural aromatic amino acids are useful tools in drug discovery, since their insertion in bioactive peptide sequences can change the side chains spatial orientation, the backbone conformation and above all, their bioactivity. In this communication, we propose a straightforward method to synthesize 2′,6′-dimethyl-tyrosine and 2′,6′-dimehylphenyl-alanine derivatives as handling building blocks for peptide synthesis via unsaturated diketopiperazine (DKP) intermediate.

A practical and convenient Blanc-type chloromethylation catalyzed by zinc chloride under solvent-free conditions

Chloromethylation of various aromatic hydrocarbons and substituted phenolic derivatives with dimethoxymethane and chlorosulfonic acid was carried out in the presence of 10 mol% of ZnCl2 in a mild and efficient manner under solvent-free conditions. In addition, 2,6-dimethyltyrosine was synthesized in high yield via this protocol.

Resolution method and application of 6- 2 sphingosahexanoic acid ester (I) as well as preparation method and application thereof (by machine translation)

The preparation method comprises the following steps 2: 6 - 2 preparing the racemic mixture of the dimethyl-L-tyrosine 2 through dynamic kinetic resolution, 6 - and then carrying out 2 dynamic kinetic resolution to obtain the compound salt 6 - of L-tyrosi