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2,6-Dimethyl-4-hydroxybenzaldehyde, also known as para-anisaldehyde, is an aromatic aldehyde with a distinctive sweet, anise-like smell. It is characterized by the presence of two methyl groups attached to carbon-2 and carbon-6, and a hydroxyl group attached to carbon-4 of the benzene ring. This chemical compound has a boiling point of 114-117 °C and a melting point of 56-60 °C. Its synthesis can be achieved through the reaction of 2,6-Dimethylphenol with formic acid.

70547-87-4

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70547-87-4 Usage

Uses

Used in Fragrance Industry:
2,6-Dimethyl-4-hydroxybenzaldehyde is used as a fragrance ingredient for its sweet, anise-like aroma, adding a pleasant scent to various products such as perfumes, cosmetics, and personal care items.
Used in Pharmaceutical Industry:
2,6-Dimethyl-4-hydroxybenzaldehyde is used as an intermediate in the synthesis of other chemicals, playing a crucial role in the development of pharmaceutical products.
Used in Cosmetic Industry:
In the cosmetic industry, 2,6-Dimethyl-4-hydroxybenzaldehyde is used as an intermediate for the production of various cosmetic ingredients, contributing to the formulation of skincare, haircare, and other beauty products.

Check Digit Verification of cas no

The CAS Registry Mumber 70547-87-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,5,4 and 7 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 70547-87:
(7*7)+(6*0)+(5*5)+(4*4)+(3*7)+(2*8)+(1*7)=134
134 % 10 = 4
So 70547-87-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H10O2/c1-6-3-8(11)4-7(2)9(6)5-10/h3-5,11H,1-2H3

70547-87-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,6-Dimethyl-4-hydroxybenzaldehyde

1.2 Other means of identification

Product number -
Other names 4-hydroxy-2,6-dimethylbenzaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:70547-87-4 SDS

70547-87-4Relevant academic research and scientific papers

Efficient synthesis and Suzuki cross-coupling reactions of meso-tetrakis(2,6-dimethyl-4-triflyloxyphenyl)porphyrin

Taesch, Julien,Dang, Tung T.,Heitz, Valérie

, p. 333 - 337 (2012)

An ortho-dimethyl substituted meso-tetrakisarylporphyrin prefunctionalized with triflate groups was prepared in good yield from an accessible 2,6-dimethyl-4-(triflyloxy)benzaldehyde. This porphyrin is an interesting building block, which could directly be

Preparation of BODIPY probes for multicolor fluorescence imaging studies of membrane dynamics

Yamada,Toyota,Takakura,Ishimaru,Sugawara

, p. 667 - 669 (2001)

Three different colored fluorescent fatty acids containing BODIPY with extremely high fluorescence quantum yields have been synthesized as probes for investigating the dynamics of membranes. Colored vesicles containing each probe, which were located in th

Synthesis of γ-labeled nucleoside 5′-triphosphates using click chemistry

Serdjukow,Kink,Steigenberger,Tomas-Gamasa,Carell

, p. 1861 - 1863 (2014)

Real-time enzymatic studies are gaining importance as their chemical and technical instrumentation improves. Here we report the efficient synthesis of γ-alkyne modified triphosphate amidates that are converted into a variety of γ-fluorophore labeled triph

Direct formylation of fluorine-containing aromatics with dichloromethyl alkyl ethers

Warashina, Takuya,Matsuura, Daisuke,Kimura, Yoshikazu

, p. 587 - 593 (2019/07/22)

Formylations of fluorine-containing aromatic compounds with dichloromethyl alkyl ethers have been investigated. Dichloromethyl propyl ether and dichloromethyl butyl ether have been applied for the formylation of fluorine-containing anisoles to give the corresponding aldehydes in good yields. Application of these ethers is preferable to that of methyl ether, which is prepared from volatile methyl formate. Reaction of fluorine-containing phenols with these dichloromethyl alkyl ethers did not give salicylaldehyde derivatives, leading instead to corresponding aryl formates in high yields. A plausible mechanism is discussed.

New Acyloxymethyl Ketones: Useful Probes for Cysteine Protease Profiling

Coman, Anca G.,Paraschivescu, Codruta C.,Hadade, Niculina D.,Juncu, Andrei,Vlaicu, Ovidiu,Popescu, Costin-Ioan,Matache, Mihaela

, p. 3917 - 3923 (2016/11/11)

Peptidyl-acyloxymethyl ketones (AOMKs) belong to a class of selective, irreversible inhibitors (activity-based probes) widely used as chemical tools of investigating proteins, for example, in activity-based protein profiling. The synthesis of the AOMKs has always been challenging and current methodologies involve both solution and solid-phase synthesis. Herein, the synthesis of a new scaffold useful for the preparation of peptidyl-AOMKs is reported and it is demonstrated that the new synthetic probes bearing a 4-functionalized 2,6-dimethylbenzoate efficiently inhibit cysteine proteases like cathepsin B.

Formylation of electron-rich aromatic rings mediated by dichloromethyl methyl ether and TiCl4: Scope and limitations

Ramos-Tomillero, Iván,Paradís-Bas, Marta,De Pinho Ribeiro Moreira, Ibério,Bofill, Josep María,Nicolás, Ernesto,Albericio, Fernando

supporting information, p. 5409 - 5422 (2015/05/13)

Here the aromatic formylation mediated by TiCl4 and dichloromethyl methyl ether previously described by our group has been explored for a wide range of aromatic rings, including phenols, methoxy- and methylbenzenes, as an excellent way to produce aromatic aldehydes. Here we determine that the regioselectivity of this process is highly promoted by the coordination between the atoms present in the aromatic moiety and those in the metal core.

A direct and mild formylation method for substituted benzenes utilizing dichloromethyl methyl ether-silver trifluoromethanesulfonate

Ohsawa, Kosuke,Yoshida, Masahito,Doi, Takayuki

, p. 3438 - 3444 (2013/06/26)

A silver trifluoromethanesulfonate (AgOTf)-promoted direct and mild formylation of benzenes has been developed. The reaction utilizing dichloromethyl methyl ether (Cl2CHOMe) and AgOTf powerfully formylated various substituted benzenes under temperature conditions as low as -78 C without losing the protecting groups on the phenolic hydroxyl group.

Compounds useful as neuro-protective agents

-

, (2008/06/13)

This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.

Method for treating pain

-

, (2008/06/13)

The present invention provides a method for treating pain using a composition comprising certain phenyl oxazoles or phenyl thiazoles in combination with a Drug Useful in the Treatment of Pain.

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