80283-74-5Relevant academic research and scientific papers
Copper-Catalyzed Decarboxylative Functionalization of Conjugated β, Γ-Unsaturated Carboxylic Acids
Zhang, Wei,Wang, Chengming,Wang, Qiu
, p. 13179 - 13185 (2020/11/17)
Copper-catalyzed decarboxylative coupling reactions of conjugated β,γ-unsaturated carboxylic acids have been achieved for allylic amination, alkylation, sulfonylation, and phosphinoylation. This approach was effective for a broad scope of amino, alkyl, su
Regiocontrolled synthesis of α-sulfonylmethyl o-nitrostyrenes via ZnI2-mediated sulfonylation and AgNO2/Pd(PPh3)4-promoted o-nitration
Chang, Meng-Yang,Chen, Han-Yu,Wang, Heui-Sin
, p. 10601 - 10610 (2018/05/31)
We report herein the AgNO2/Pd(PPh3)4-promoted regiocontrolled o-nitration of α-sulfonylmethylstyrenes in MeNO2 with good yields. The o-nitration process provides a series of sulfonyl o-nitrostyrenes. Substituted α-sulfonylmethylstyrenes were synthesized from ZnI2-mediated sulfonylation of substituted α-methylstyrenes and sodium sulfinates (RSO2Na) in MeCN with good to excellent yields. The structures of the key products were confirmed by X-ray crystallography. A plausible mechanism has been proposed herein.
Sulfonylative alkoxyhydroxylation of 2-arylpropenes
Wang, Huei-Sin,Wu, Yan-Shin,Chang, Meng-Yang
, p. 6465 - 6470 (2017/10/10)
One-pot three-step sulfonylative alkoxyhydroxylation of 2-arylpropenes 1 affords oxygenated sulfonylcumenes 4 in moderate yields via a sequential route: (i) NBS-mediated allylic bromination of 2-arylpropenes 1 in CH2Cl2, (ii) sodium sulfinates 2-promoted nucleophilic substitution of the resulting styryl bromides in a co-solvent of alcohol and water, and (iii) V2O5/H2O2 mediated alkoxyhydroxylation of corresponding styryl sulfones 3 in alcohol. The synthetic route provides a highly effective protocol for the 1,2,3-tricarbofunctionalization of 2-arylpropenes 1 via two carbon-oxygen and one carbon-sulfur bond formations.
Visible-light induced oxidant-free oxidative cross-coupling for constructing allylic sulfones from olefins and sulfinic acids
Zhang, Guoting,Zhang, Lingling,Yi, Hong,Luo, Yi,Qi, Xiaotian,Tung, Chen-Ho,Wu, Li-Zhu,Lei, Aiwen
supporting information, p. 10407 - 10410 (2016/09/02)
An oxidant-free dehydrogenative sulfonylation of α-methyl-styrene derivatives was developed for the construction of allylic sulfones by using eosin Y as a photosensitizer in conjunction with a cobaloxime catalyst. The process features a low-cost metal catalyst and atom economy, which provides an appealing strategy for future synthetic chemistry.
SYNTHESIS AND ALKYLATION OF VINYLSULFINIC ACIDS VIA FLUORIDE CLEAVAGE OF β-TRIMETHYLSILYLETHYL VINYL SULFONES
Palmer, James T.,Fuchs, P. L.
, p. 233 - 246 (2007/10/02)
A new method for the synthesis of vinylsulfinic acids from aldehydes is described.The homologated vinyl (trimethylsilylethyl)sulfones were synthesized from the corresponding aldehydes by means of the phosphonium salt derived from the chloromethylsulfide o
