80301-56-0

Basic information

• Product Name: 4-nitrobenzylmaleimide
• Synonyms: 4-nitrobenzylmaleimide
• CAS NO: 80301-56-0
• Molecular Formula: C₁₁H₁₀N₂O₄
• Molecular Weight: 234.2081
• Mol File: 80301-56-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 489.8°Cat760mmHg
• Flash Point: 250°C
• Appearance: /
• Density: 1.437g/cm³
• Vapor Pressure: 9.69E-10mmHg at 25°C
• Refractive Index: 1.63
• CAS DataBase Reference: 4-nitrobenzylmaleimide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-nitrobenzylmaleimide(80301-56-0)
• EPA Substance Registry System: 4-nitrobenzylmaleimide(80301-56-0)

Safety Data

• Hazardous Substances Data: 80301-56-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H10N2O4/c14-10-5-6-11(15)12(10)7-8-1-3-9(4-2-8)13(16)17/h1-4H,5-7H2

Upstream product

• 2142-06-5 1-(phenylmethyl)-2,5-pyrrolidinedione 
• 7697-37-2 nitric acid 
• 516-12-1 N-iodo-succinimide 
• 104-03-0 4-nitrobenzeneacetic acid 
• 123-56-8 Succinimide 
• 100-14-1 4-nitrobenzyl chloride 

Relevant articles and documents

One-Pot Transformation of Aliphatic Carboxylic Acids into N-Alkylsuccin-imides with NIS and NCS/NaI

Primary aliphatic carboxylic acids were treated with N-iodosuccinimide (NIS) in 1,2-dichloroethane to form the corresponding alkyl iodides under warming conditions. Based on these results, those aliphatic carboxylic acids were treated with NIS, followed by the reaction with K2CO3to give the corresponding N-alkylsuccinimides in good yields in one pot. Moreover, those aliphatic carboxylic acids were treated with N-chlorosuccinimide (NCS) and NaI, followed by the reaction with K2CO3to provide the corresponding N-alkylsuccinimides in good to moderate yields in one pot. By using the present method, successive treatment of primary aliphatic carboxylic acids (10 mmol) with NIS, K2CO3, and then hydrazine provided the corresponding decarboxylated primary amines in good yield.