80304-52-5Relevant academic research and scientific papers
A Series of 2-((1-Phenyl-1H-imidazol-5-yl)methyl)-1H-indoles as Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors
Zheng, Yong,Stafford, Paul M.,Stover, Kurt R.,Mohan, Darapaneni Chandra,Gupta, Mayuri,Keske, Eric C.,Schiavini, Paolo,Villar, Laura,Wu, Fan,Kreft, Alexander,Thomas, Kiersten,Raaphorst, Elana,Pasangulapati, Jagadeesh P.,Alla, Siva R.,Sharma, Simmi,Mittapalli, Ramana R.,Sagamanova, Irina,Johnson, Shea L.,Reed, Mark A.,Weaver, Donald F.
supporting information, p. 2195 - 2205 (2021/05/31)
Indoleamine 2,3-dioxygenase 1 (IDO1) is a promising therapeutic target in cancer immunotherapy and neurological disease. Thus, searching for highly active inhibitors for use in human cancers is now a focus of widespread research and development efforts. I
CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF
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Paragraph 1361, (2018/04/17)
Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.
ARYL GPR120 RECEPTOR AGONISTS AND USES THEREOF
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Page/Page column 68-69, (2010/05/13)
Aryl GPR120 agonists are provided. These compounds are useful for the treatment of metabolic diseases, including Type II diabetes and diseases associated with poor glycemic control.
A new facile method for the synthesis of 1-arylimidazole-5-carboxylates
Chen, Bang-Chi,Bednarz, Mark S.,Zhao, Rulin,Sundeen, Joseph E.,Chen, Ping,Shen, Zhongqi,Skoumbourdis, Amanda P.,Barrish, Joel C.
, p. 5453 - 5456 (2007/10/03)
A new facile method for the preparation of 1-arylimidazole-5- carboxylates was developed. The new method involved reaction of anilines and ethyl glyoxylate in methanol to give α-anilino-α-methoxyacetates followed by cyclization with TosMIC, affording 1-ar
