80365-68-0

Basic information

• Product Name: 1-benzyl-2-benzoylpyrrolidine
• Synonyms: 1-benzyl-2-benzoylpyrrolidine
• CAS NO: 80365-68-0
• Molecular Weight: 265.355
• Mol File: 80365-68-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-benzyl-2-benzoylpyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-2-benzoylpyrrolidine(80365-68-0)
• EPA Substance Registry System: 1-benzyl-2-benzoylpyrrolidine(80365-68-0)

Safety Data

• Hazardous Substances Data: 80365-68-0(Hazardous Substances Data)

Upstream product

• 7730-39-4 N-benzyl azetidine 
• 3282-32-4 2-diazo-acetophenone 
• 60169-72-4 1-benzyl-pyrrolidine-2-carboxylic acid 

Downstream Products

• 5291-77-0 1-benzyl-2-pyrrolidone 
• 65-85-0 benzoic acid 

Relevant articles and documents

Palladium-catalyzed asymmetric allylic alkylation of acyclic ketones for synthesis of 2,2-disubsituted pyrrolidine derivatives

Palladium-catalyzed asymmetric allylic alkylation of acyclic ketones represents a significant challenge in organic synthesis. We report herein that the synthesis of chiral 2,2-disubsituted pyrrolidines from acyclic ketones has been accomplished by using catalytic asymmetric method in the presence of Pd(dba)2 and (R)-binap ligand. Theses reactions occur between allyl methyl carbonate and unstabilized acyclic lithium enolates to provide the products in moderate to good enantioselectivity (up to 81% ee).