804476-56-0Relevant academic research and scientific papers
Conversion of thiobenzamides to benzothiazoles via intramolecular cyclization of the aryl radical cation
Downer-Riley, Nadale K.,Jackson, Yvette A.
, p. 7741 - 7744 (2008/12/20)
A new and general method has been developed for the intramolecular cyclization of thiobenzamides to benzothiazoles via aryl radical cations as reactive intermediates. The method utilizes phenyliodine(III) bis(trifluoroacetate) (PIFA) in trifluoroethanol or cerium ammonium nitrate (CAN) in aqueous acetonitrile at room temperature to effect cyclization within 30 min in moderate yields.
Synthesis of benzothiazoles via ipso substitution of ortho- methoxythiobenzamides
Downer, Nadale K.,Jackson, Yvette A.
, p. 3039 - 3043 (2007/10/03)
An efficient route to the synthesis of benzothiazoles from orthoo-methoxythiobenzamides via the ipso substitution of an aromatic methoxy group is presented, and the mechanism of the Jacobson synthesis of benzothiazoles is further investigated.
