80537-14-0

Basic information

• Product Name: PYRAZOLO[1,5-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
• Synonyms: ETHYL PYRAZOLO[1,5-A]PYRIDINE-2-CARBOXYLATE;PYRAZOLO[1,5-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER;1H-Pyrazolo[1,5-a]pyridine-2-carboxylic acid ethyl ester
• CAS NO: 80537-14-0
• Molecular Formula: C₁₀H₁₀N₂O₂
• Molecular Weight: 190.2
• Product Categories: pharmacetical
• Mol File: 80537-14-0.mol
• Article Data: 8

Chemical Properties

• Melting Point: 47-48℃
• Appearance: /
• Density: 1.22
• Refractive Index: 1.608
• Storage Temp.: 2-8°C
• CAS DataBase Reference: PYRAZOLO[1,5-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: PYRAZOLO[1,5-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER(80537-14-0)
• EPA Substance Registry System: PYRAZOLO[1,5-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER(80537-14-0)

Safety Data

• Hazardous Substances Data: 80537-14-0(Hazardous Substances Data)

Usage

General Description

PYRAZOLO[1,5-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER is a chemical compound with the molecular formula C9H8N4O2. It is an ethyl ester derivative of pyrazolo[1,5-a]pyridine-2-carboxylic acid and is often used in medicinal chemistry and drug development. PYRAZOLO[1,5-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER is a heterocyclic compound with potential biological activity, and it is studied for its potential pharmacological properties. It is important to handle and use this compound with appropriate safety measures, as it may have potential hazards associated with its handling and use.

InChI:InChI=1/C9H8N2O2/c1-13-9(12)8-6-7-4-2-3-5-11(7)10-8/h2-6H,1H3

Upstream product

• 64-17-5 ethanol 
• 201230-82-2 carbon monoxide 
• 59942-87-9 2-hydroxypyrazolo<1,5-α>pyridine 
• 63237-87-6 pyrazolo[1,5-a]pyridine-2,3-dicarboxylic acid 
• 1121-60-4 pyridine-2-carbaldehyde 
• 63237-88-7 pyrazolo[1,5-a]pyridine-2-carboxylic acid 
• 81803-59-0 ethyl 2-azido-3-(2-pyridyl)propenoate 
• 5825-71-8 pyrazolo<1,5-a>pyridine-2,3-dicarboxylic acid dimethyl ester 

Downstream Products

• 885275-10-5 pyrazolo[1,5-a]pyridine-2-carbaldehyde 
• 337972-47-1 FAUC 213 
• 151831-22-0 ethyl 3-formyl-2-pyrazolo<1,5-a>pyridinecarboxylate 

Relevant articles and documents

HETEROCYCLE-SUBSTITUTED TETRACYCLIC COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES

The present invention relates to novel Heterocycle-Substituted Tetracyclic Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, A', R2 R3 and R5 are as defined herein. The present invention also relates to compositions comprising at least one Heterocycle-Substituted Tetracyclic Compound, and methods of using the Heterocycle-Substituted Tetracyclic Compounds for treating or preventing HCV infection in a patient.

4- [HETEROCYCLYL-METHYL] -8-FLUORO-QUINOLIN-2-ONES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS

Novel compounds of formulae (II, III) and pharmaceutical compositions have been found to inhibit inducible NOS synthase wherein: R4, R5, R6 and R7 are independently selected from the group consisting of hydrogen, lower alkyl, and halogen; and, R8 has the structure whrein X1, X2, X3, X4, X5, X6, R9, R13, R14 and n are as described herein.

Rationally based efficacy tuning of selective dopamine D4 receptor ligands leading to the complete antagonist 2-[4-(4-Chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-α]pyridine (FAUC 213)

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