80588-64-3

Upstream product

• 434-64-0 perfluorotoluene 
• 651-83-2 4-trifluoromethyl-2,3,5,6-tetrafluoroaniline 
• 65-85-0 benzoic acid 

Downstream Products

• 1300857-15-1 2-morpholino-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)benzamide 
• 1327280-66-9 C₂₁H₁₂F₇NO 
• 1344685-85-3 2-fluoro-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)benzamide 
• 1344686-02-7 2,6-difluoro-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)benzamide 
• 1327280-84-1 N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-2-(trifluoromethyl)benzamide 
• 1446442-52-9 2,6-diiodo-N-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]benzamide 
• 1446442-53-0 3,3'-diiodo-N²,N²-bis[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]-(1,1'-biphenyl)-2,2'-dicarboxamide 
• 1352238-69-7 C₁₄H₆F₇NO₂ 
• 93-89-0 benzoic acid ethyl ester 
• 1465827-32-0 2,6-di-morpholino-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)benzamide 
• 1352238-53-9 (CH₃)4C₂O₂BC₆H₄CONHC₆F₄CF₃ 
• 1352238-73-3 C₁₄H₅BrF₇NO 
• 1352238-72-2 C₂₀H₁₁F₇N₂O 
• 1352238-71-1 C₁₇H₁₃F₇N₂O 

Relevant academic research and scientific papers

Palladium-Catalyzed Electrochemical C-H Bromination Using NH4Br as the Brominating Reagent

The palladium-catalyzed electrochemical C-H bromination of benzamide derivatives under divided cells is developed, in which NH4Br serves as a brominating reagent and electrolyte. The protocol avoids the use of chemical oxidants and provides an alternative method for the synthesis of aryl bromides.

PALLADIUM(II)-CATALYZED SELECTIVE FLUORINATION OF BENZOIC ACIDS AND DERIVATIVES

A new method of ortho-fluorination for selectively fluorinating a benzoic acid or derivative compound where an aryl C—H bond is directly replaced by an aryl C—F bond is provided. The method comprises reacting a compound having the formula: wherein X is at

Palladium(II)-catalyzed selective monofluorination of benzoic acids using a practical auxiliary: A weak-coordination approach

Finally, a choice! A highly selective palladium(II)-catalyzed ortho-monofluorination reaction has been achieved for the first time through a weak coordination (see scheme; Ar=2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl) . Simple modification of this protocol allows for a choice between mono- and difluorination. The mono- and difluorinated benzoic acid derivatives are valuable in the pharmaceutical and agrochemical industries. Copyright

Pd(II)-catalyzed cross-coupling of C(sp2)h bonds and alkyl, aryl, and vinylboron reagents via Pd(II)/Pd(0) catalysis

Pd(II)-catalyzed cross-coupling of ortho-CH bonds in benzoic acid and phenylacetic acid amides with alkyl, aryl, and vinylboron reagents have been achieved via Pd(II)/Pd(0) catalysis, demonstrating the unprecedented versatility of CH activation reactions.