80737-85-5

Basic information

• Product Name: [(2-oxo-2-phenylethyl)sulfanyl]acetonitrile
• CAS NO: 80737-85-5
• Molecular Formula: C₁₀H₉NOS
• Molecular Weight: 191.2496
• Mol File: 80737-85-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 344.7°C at 760 mmHg
• Flash Point: 162.3°C
• Density: 1.185g/cm³
• Vapor Pressure: 6.48E-05mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: [(2-oxo-2-phenylethyl)sulfanyl]acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: [(2-oxo-2-phenylethyl)sulfanyl]acetonitrile(80737-85-5)
• EPA Substance Registry System: [(2-oxo-2-phenylethyl)sulfanyl]acetonitrile(80737-85-5)

Safety Data

• Hazardous Substances Data: 80737-85-5(Hazardous Substances Data)

Usage

General Description

[(2-oxo-2-phenylethyl)sulfanyl]acetonitrile is a chemical compound with the molecular formula C10H9NO2S. It is a nitrile derivative containing a phenyl group and a thioether group. [(2-oxo-2-phenylethyl)sulfanyl]acetonitrile is commonly used as a building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. It is known for its potential biological activity and is being studied for its anti-cancer and anti-inflammatory properties. However, [(2-oxo-2-phenylethyl)sulfanyl]acetonitrile has not been extensively studied and further research is needed to fully understand its potential uses and effects.

Upstream product

• 107-14-2 chloroacetonitrile 
• 22651-09-8 N-methyl-N-<<(2-oxo-2-phenylethyl)thio>methylene>methanaminium bromide 
• 54524-31-1 2-mercaptoacetonitrile 
• 532-27-4 1-chloroacetophenone 
• 2462-02-4 2-mercaptoacetophenone 
• 590-17-0 cyanomethyl bromide 
• 98-86-2 acetophenone 
• 53392-49-7 phenacyl thioacetate 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 80737-87-7 2-cyano-3,6-dihydro-5-<oxy>-2H-thiopyran 
• 81134-59-0 2-cyano-3,6-dihydro-4-<oxy>-2H-thiopyran 
• 98-86-2 acetophenone 
• 73496-60-3 4-Ethoxy-3,6-dihydro-2H-thiopyran-2-carbonitrile 
• 81134-58-9 2-cyano-3,6-dihydro-4-ethoxy-2H-thiopyran 

Relevant articles and documents

Continuous Flow Synthesis of 2H-Thiopyrans via thia-Diels–Alder Reactions of Photochemically Generated Thioaldehydes

Herein, we report a novel protocol for the photochemical generation of thioaldehydes in a continuous flow process which were in situ reacted with electron rich 1,3-butadienes in thia-Diels–Alder reactions. A broad range of 3,6-dihydro-2H-thiopyrans were formed as products in much higher yields and productivities as compared to classical batch processes. Moreover, greatly reduced reaction times and a facile large-scale preparation of products were achieved by fully exploiting the advantages of continuous flow technology.

Thioaldehyde Diels-Alder Reactions

Thioaldehydes containing virtually any α-substitutent can be generated by photofragmentation of phenacyl sulfides.Donor-substituted derivatives are reactive toward electron-rich dienes and give 2 + 4 cycloadducts with regiochemistry corresponding to advan

Dienophilic Thioaldehydes

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