80737-85-5

Usage

Uses

Used in Pharmaceutical Industry:
[(2-oxo-2-phenylethyl)sulfanyl]acetonitrile is used as a building block in the synthesis of various pharmaceuticals. Its unique structure allows for the creation of a wide range of compounds with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, [(2-oxo-2-phenylethyl)sulfanyl]acetonitrile is utilized as a starting material for the development of new agrochemicals, such as pesticides and herbicides, due to its versatile chemical structure.
Used in Organic Synthesis:
[(2-oxo-2-phenylethyl)sulfanyl]acetonitrile is also employed in organic synthesis as an intermediate for the production of various organic compounds, taking advantage of its reactive functional groups.
Used in Cancer Research:
[(2-oxo-2-phenylethyl)sulfanyl]acetonitrile is being studied for its potential anti-cancer properties. Its biological activity is of interest to researchers, who are investigating its effects on cancer cells and its potential role in the development of new cancer treatments.
Used in Inflammation Research:
Additionally, [(2-oxo-2-phenylethyl)sulfanyl]acetonitrile is being explored for its anti-inflammatory properties, which could lead to its use in the development of new treatments for inflammatory conditions.

Upstream product

• 107-14-2 chloroacetonitrile 
• 22651-09-8 N-methyl-N-<<(2-oxo-2-phenylethyl)thio>methylene>methanaminium bromide 
• 2462-02-4 2-mercaptoacetophenone 
• 590-17-0 cyanomethyl bromide 
• 98-86-2 acetophenone 
• 53392-49-7 phenacyl thioacetate 
• 70-11-1 α-bromoacetophenone 
• 54524-31-1 2-mercaptoacetonitrile 
• 532-27-4 1-chloroacetophenone 

Downstream Products

• 73496-60-3 4-Ethoxy-3,6-dihydro-2H-thiopyran-2-carbonitrile 
• 81134-58-9 2-cyano-3,6-dihydro-4-ethoxy-2H-thiopyran 
• 98-86-2 acetophenone 
• 80737-87-7 2-cyano-3,6-dihydro-5-<oxy>-2H-thiopyran 
• 81134-59-0 2-cyano-3,6-dihydro-4-<oxy>-2H-thiopyran 

Relevant academic research and scientific papers

Continuous Flow Synthesis of 2H-Thiopyrans via thia-Diels–Alder Reactions of Photochemically Generated Thioaldehydes

Herein, we report a novel protocol for the photochemical generation of thioaldehydes in a continuous flow process which were in situ reacted with electron rich 1,3-butadienes in thia-Diels–Alder reactions. A broad range of 3,6-dihydro-2H-thiopyrans were formed as products in much higher yields and productivities as compared to classical batch processes. Moreover, greatly reduced reaction times and a facile large-scale preparation of products were achieved by fully exploiting the advantages of continuous flow technology.

Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis

The present invention provides compounds of Formula I, STR1 or a pharmaceutically acceptable salt forms thereof, which are inhibitors of acyl-Coenzyme A: cholesterol O-acyltransferase (ACAT), pharmaceutical compositions containing such compounds, processes for the preparation of such compounds, and the use of such compounds as antihypercholesterolemic and/or antiatherosclerotic agents.

Thioaldehyde Diels-Alder Reactions

Thioaldehydes containing virtually any α-substitutent can be generated by photofragmentation of phenacyl sulfides.Donor-substituted derivatives are reactive toward electron-rich dienes and give 2 + 4 cycloadducts with regiochemistry corresponding to advan

Synthesis of Unsymmetrical Functionalised Organic Sulphides

Acyclic thioiminium salts and the condensed thiazolium salts in the presence of aqueous sodium hydroxide as such or under base catalyzed phase transfer catalysis conditions react with appropiate organic halides to provide corresponding unsymmetrical functionalized organic sulphides.With aqueous sodium hydroxide, thioiminium salts provide the disulphides corresponding to incipient thiol.