80746-22-1

Upstream product

• 52215-24-4 N'-(2,4-dibromophenyl)benzothiohydrazide 
• 85921-07-9 3-(2,4-Dibromo-phenyl)-2-[3-(2,4-dibromo-phenyl)-5-phenyl-3H-[1,3,4]thiadiazol-(2Z)-ylidenemethyl]-2-methyl-5-phenyl-2,3-dihydro-[1,3,4]thiadiazole 
• 57279-86-4 N'-acetyl-N'-(2,4-dibromophenyl)benzothiohydrazide 
• 507-09-5 tiolacetic acid 
• 123-54-6 acetylacetone 
• 80869-95-0 3-(2,4-dibromophenyl)-2,3-dihydro-5-phenyl-2-thioacetylmethylene-1,3,4-thiadiazole 
• 108-24-7 acetic anhydride 
• 85921-06-8 3-(2,4-dibromophenyl)-2,3-dihydro-2-methoxy-2-methyl-5-phenyl-1,3,4-thiadiazole 
• 674-82-8 4-methyleneoxetan-2-one 

Downstream Products

• 80869-95-0 3-(2,4-dibromophenyl)-2,3-dihydro-5-phenyl-2-thioacetylmethylene-1,3,4-thiadiazole 

Relevant academic research and scientific papers

A 2-methylthio-3,5-diaryl-1,3,4-thiadiazolium cation; its reactions, and further exploration of the chemistry of 2-alkyl-3,5-diaryl-1,3,4-thiadiazolium cations

Activation of a representative 3,5-diaryl-1,3,4-thiadiazole-2-thione by thione S-methylation gives a cation that is readily susceptible to nucleophilic substitution.Reactions with diethyl malonate, ethyl acetoacetate, acetylacetone, cyclopentan-1,3-dione, or 3-ethylrhodanine under basic conditions led to β,β-disubstituted methine bases and (or) β-substituted methine bases in cases where deacetylation occurs under the reaction conditions.This cation and the 2-alkyl-3,5-diaryl-1,3,4-thiadiazolium cation are convenient sources of a series of neutral and cationic dyes containing the 1,3,4-thiadiazole ring system.

2-Alkyl-3,5-diaryl-1,3,4-thiadiazolium Perchlorates and Reactions thereof

2-Alkyl- and 2-aryl-3,5-diaryl-1,3,4-thiadiazolium perchlorates can be prepared from N'-arylbenzothiohydrazides by reaction with (a) a carboxylic anhydride-perchloric acid mixture or (b) a nitrile-perchloric acid mixture.The 2-methyl-3,5-diaryl-1,3,4-thia

Acylation of N'-Arylbenzothiohydrazides and of their N'-Acyl-derivatives; 2-Acylalkylidene-3-aryl-5-phenyl-2H-1,3,4-thiadiazolenes and Related Compounds

Reactions of N'-arylbenzothiohydrazides and of their N-acyl-derivatives with carboxylic anhydrides under various sets of conditions are shown to lead to 2-acylalkylidene-3-aryl-5-phenyl-2H-1,3,4-thiadiazolenes.The probable mechanism of formation of these compounds via the corresponding 2-alkylidenethiadiazolene as intermediate is discussed.

Routes to 3-Aryl-5-phenyl-2-thioacylmethylene-2H-1,3,4-thiadiazolenes

Prospective routes to the above compounds include reaction of an N'-arylbenzothiohydrazide or of its N'-acetyl derivative with thioacetic acid, when the thioacyl and acyl derivatives are formed, as well as by reaction of the 2-acylmethylene-3-aryl-5-pheny