80800-66-4Relevant academic research and scientific papers
Identification and Enantiodivergent Synthesis of (5 Z,9 S)-Tetradec-5-en-9-olide, a Queen-Specific Volatile of the Termite Silvestritermes minutus
Machara, Ale?,K?ivánek, Jan,Dolej?ová, Klára,Havlí?ková, Jana,Bednárová, Lucie,Hanus, Robert,Majer, Pavel,Kyjaková, Pavlína
, p. 2266 - 2274 (2018/10/20)
The queens of social insects differ from sterile colony members in many aspects of their physiology. Besides adaptations linked with their specialization for reproduction and extended lifespan, the queens also invest in the maintenance of their reproducti
Synthesis of the C(7)-C(22) Sector of (+)-Acutiphycin via O-directed double free radical alkyne hydrostannation with Ph3SnH/Et3B, double I-Sn exchange, and double stille coupling
Hale, Karl J.,Maczka, Maciej,Kaur, Amarjit,Manaviazar, Soraya,Ostovar, Mehrnoosh,Grabski, Milosz
, p. 1168 - 1171 (2014/03/21)
Herein a new double O-directed free radical hydrostannation reaction is reported on the structurally complex dialkyldiyne 11. Through our use of a conformation-restraining acetal to help prevent stereocenter-compromising 1,5-H-atom abstraction reactions b
Synthesis of prostaglandin and phytoprostane B1 via regioselective intermodular pauson-khand reactions
Vazquez-Romero, Ana,Cardenas, Lydia,Blasi, Emma,Verdaguer, Xavier,Riera, Antoni
scheme or table, p. 3104 - 3107 (2009/12/05)
A new approach to the synthesis of prostaglandin and phytoprostanes B 1 is described. The key step is an intermolecular Pauson-Khand reaction between a silyl-protected propargyl acetylene and ethylene. This reaction, promoted by NMO in the presence of 4 A molecular sieves, afforded the 3-fert-butyldimethylsilyloxymethyl-2-substituted-cyclopent-2-en-1- ones (III) in good yield and with complete regioselectivity. Deprotection of the silyl ether, followed by Swern oxidation, gave 3-formyl-2-substituted- cyclopent-2-en-1-ones (II). Julia olefination of the aldehydes II with the suitable chiral sulfone enabled preparation of PPB1 type I and PGB1.
Syntheses of the macrolide subunits of merremoside-type resin glycosides
Zhu, Xing-Mei,He, Li-Li,Yang, Guang-Li,Lei, Ming,Chen, Si-Shi,Yang, Jin-Song
, p. 3510 - 3512 (2007/10/03)
The 20- and 21-membered macrolide subunits of merremoside-type resin glycosides with interesting bioactivity were synthesized via a macrolactonization approach using Corey-Nicolaou protocol in 14 steps with overall yields of 0.7% for 17 and 3.5% for 18 fr
Fluorine-containing optically active compound and liquid crystal composition containing the same
-
, (2008/06/13)
A fluorine-containing optically active compound represented by formula (I): STR1 wherein R1 represents a straight chain alkyl or alkoxy group having from 6 to 14 carbon atoms or a 4-alkylphenyl or 4-alkoxyphenyl group having from 8 to 12 carbon
Prostaglandins. 2. Synthesis of Prostaglandin F2α in Optically Active Form from Chiral Precursors
Johnson, Francis,Paul, K.G.,Favara, Duccio,Ciabatti, Romeo,Guzzi, Umberto
, p. 2190 - 2198 (2007/10/02)
A synthetic route to optically active prostaglandins is described which use chiral starting materials.Acylation of the bis(magnesiobromide) salt of methyl hemimalonate with (S)-(-)-2-acetoxysuccinyl chloride led to unstable dimethyl (S)-4-acetoxy-3,6-diox
