3710-31-4

Basic information

• Product Name: 1,2-HEPTANEDIOL
• Synonyms: 1,2-HEPTANEDIOL;1,2-DIHYDROXYHEPTANE;1,2-HEPTANEDIOL 96+%;HEPTANE-1,2-DIOL;Heptane-1,2-doil
• CAS NO: 3710-31-4
• Molecular Formula: C₇H₁₆O₂
• Molecular Weight: 132.2
• Mol File: 3710-31-4.mol
• Article Data: 6

Chemical Properties

• Melting Point: 44.24°C (estimate)
• Boiling Point: 130 °C / 11mmHg
• Flash Point: 101.7°C
• Appearance: /
• Density: 0.94
• Vapor Pressure: 0.016mmHg at 25°C
• Refractive Index: 1.4430 to 1.4470
• CAS DataBase Reference: 1,2-HEPTANEDIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-HEPTANEDIOL(3710-31-4)
• EPA Substance Registry System: 1,2-HEPTANEDIOL(3710-31-4)

Safety Data

• Hazardous Substances Data: 3710-31-4(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 27, p. 4343, 1986 DOI: 10.1016/S0040-4039(00)94270-9

InChI:InChI=1/C7H16O2/c1-2-3-4-5-7(9)6-8/h7-9H,2-6H2,1H3

Upstream product

• 154802-30-9 (±)-2,3-epoxy-1-heptanol 
• 592-76-7 1-Heptene 
• 110-83-8 cyclohexene 
• 142-82-5 n-heptane 
• 1191-15-7 diisobutylaluminium hydride 
• 138051-65-7 ((2S,3S)-3-Butyl-oxiranyl)-methanol 

Downstream Products

• 66-25-1 hexanal 
• 142-62-1 hexanoic acid 
• 39846-66-7 1-acetoxy-2-hydroxyheptane 
• 120925-79-3 (RS)-1-p-toluenesulfonyloxy-2-heptanol 
• 110549-07-0 (R)-1,2-epoxyheptane 
• 51154-96-2 (R)-massoialactone 
• 80800-66-4 (S)-2-hydroxyhept-1-yl 4-methylbenzenesulfonate 
• 39846-56-5 (R)-1,2-diacetoxyheptane 
• 78843-64-8 (2R)-heptane-1,2-diol 
• 39846-56-5 1,2-diacetoxyheptane 
• 61229-00-3 (2S)-heptane-1,2-diol 

Relevant articles and documents

Selective transition-metal-free vicinal cis-dihydroxylation of saturated hydrocarbons

A transition-metal-free cis-dihydroxylation of saturated hydrocarbons under ambient reaction conditions has been developed. The described approach allows a direct and selective synthesis of vicinal diols. The new reaction thereby proceeds via radical iodination and a sequence of oxidation steps. A broad scope of one-pot dual C(sp3)-H bond functionalization for the selective synthesis of vicinal syn-diols was demonstrated.

Regioselective epoxidation of different types of double bonds over large-pore titanium silicate Ti-β

Regioselective epoxidation of different types of double bonds located within the cyclic and acyclic parts of bulky olefins has been investigated using large-pore titanium silicate Ti-β in the presence of dilute aqueous H 2O2 as oxidant under mild liquid-phase conditions. Our experimental results revealed that side-chain vinylic double bonds are selectively epoxidized than those in the cyclohexene-ring. The epoxidation tendency of various bulky olefins with different positional and/or geometric isomers over Ti-β follows the order: terminal -CC- > ring -CC- ≈ bicyclic ring -CC- > allylic C - H bond. Unlike 4-vinyl-1-cyclohexene, epoxidation of an equimolar mixture of cyclohexene and 1-hexene under identical conditions using Ti-β exhibits completely different selectivity and product distributions. Steric factor and accessibility of reactants to active Ti-sites are responsible for the observed regioselectivity of bulky alkenes.

REGIOSELECTIVE TITANIUM MEDIATED REDUCTIVE OPENING OF 2,3-EPOXY ALCOHOLS

Lithium borohydride reduction of 2,3-epoxy alcohols was shown to yield 1,2-diols in high regioselectivity with the aid of titanium tetraisopropoxide in benzene solution.