80825-32-7Relevant articles and documents
Synthesis and anti-inflammatory activity of phenylbutenoid dimer analogs
Kim, Sung-Soo,Fang, Yuanying,Park, Haeil
supporting information, p. 1676 - 1680 (2015/07/15)
Several phenylbutenoid dimer (PBD) analogs were synthesized and evaluated for their inhibitory activities against nitric oxide (NO) production and TNF-α release. The PBD analogs were synthesized via Diels - Alder and subsequent Schlosser reactions as key steps. Among the tested compounds, two analogs (8c, 8f) exhibited much stronger inhibitory activity against LPS-stimulated NO production and TNF-α release in RAW 264.7 cells than that of wogonin.