80925-22-0

Basic information

• Product Name: (R)-(+)-5-benzyloxy-2,4-dimethyl-(E)-2-pentenol
• Synonyms: (R)-(+)-5-benzyloxy-2,4-dimethyl-(E)-2-pentenol
• CAS NO: 80925-22-0
• Molecular Weight: 220.312
• Mol File: 80925-22-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-(+)-5-benzyloxy-2,4-dimethyl-(E)-2-pentenol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-5-benzyloxy-2,4-dimethyl-(E)-2-pentenol(80925-22-0)
• EPA Substance Registry System: (R)-(+)-5-benzyloxy-2,4-dimethyl-(E)-2-pentenol(80925-22-0)

Safety Data

• Hazardous Substances Data: 80925-22-0(Hazardous Substances Data)

Upstream product

• 2749-70-4 bis(benzyloxy)methane 
• 794525-07-8 (4S,1'E,3'E)-(-1'-{[tert-butyl(dimethyl)silyl]oxy}-2'-methyl-1',3'-pentadienyl)-4-isopropyl-1,3-oxazolidin-2-one 
• 86046-97-1 [(R)-3-(1-Ethoxy-ethoxy)-2-methyl-propoxymethyl]-benzene 
• 100-39-0 benzyl bromide 
• 86046-97-1 (2R)-(-)-benzyl 3-(1'-ethoxyethoxy)-2-methylpropyl ether 
• 79026-61-2 (R)-3-benzyloxy-2-methylpropanal 
• 63930-46-1 (S)-3-benzyloxy-2-methylpropan-1-ol 
• 80885-47-8 (R)-(+)-5-benzyloxy-2,4-dimethyl-(E)-2-pentenal 

Downstream Products

• 86117-46-6 (2R,3S)-3-[(6E,8E)-(1R,2S,5R)-10-(4-Chloro-3-methoxy-5-methylamino-phenyl)-2-(1-ethoxy-ethoxy)-4,4-bis-ethylsulfanyl-5-methoxy-1,9-dimethyl-deca-6,8-dienyl]-2-methyl-oxirane-2-carbaldehyde 
• 72729-16-9 {(2S,3S)-3-[(6E,8E)-(1R,2S,5R)-10-(4-Chloro-3-methoxy-5-methylamino-phenyl)-2-(1-ethoxy-ethoxy)-4,4-bis-ethylsulfanyl-5-methoxy-1,9-dimethyl-deca-6,8-dienyl]-2-methyl-oxiranyl}-methanol 
• 52978-28-6 (-)-maysine 
• 86046-99-3 C₄₄H₇₈ClNO₈S₂Si₂ 
• 86046-99-3 C₄₄H₇₈ClNO₈S₂Si₂ 
• 86116-97-4 C₄₅H₈₀ClNO₈S₂Si₂ 

Relevant articles and documents

Stereoselective Alkylation of the Vinylketene Silyl N,O-Acetal and Its Application to the Synthesis of Mycocerosic Acid

Stereoselective alkylation of the vinylketene silyl N,O-acetal possessing a chiral auxiliary has been achieved by using activated alkyl halides including allyl iodides, benzyl iodides, and propargyl iodide with Ag(I) ion in the presence of BF3·

ENANTIOSELECTIVE SYNTHESIS OF C3-C10 FRAGMENT (NORTHEASTERN ZONE) OF MAYTANSINOIDS WITH 4-CHIRAL CENTERS (4S,5S,6R,7S)

The major precursor to the maytansinoids containing 4 non-racemic chiral centers has been prepared in gram quantities, suitable for further synthesis.The route to (+)-1 was accomplished in 13 steps including several highly stereocontrolled reactions which