80948-74-9

Usage

Uses

Used in Organic Synthesis:
(4-Bromo-3-methyl-phenyl)-methyl-amine is utilized as a building block in organic synthesis for the creation of various complex organic molecules. Its distinct functional groups and structural features allow for versatile reactions and the formation of a wide range of compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (4-Bromo-3-methyl-phenyl)-methyl-amine serves as a key intermediate in the development of new drugs. Its unique structure may contribute to the discovery of novel therapeutic agents with specific biological activities, potentially leading to advancements in medicine.
Safety Considerations:
It is crucial to handle (4-Bromo-3-methyl-phenyl)-methyl-amine with care and adhere to proper safety protocols when working with it in a laboratory setting. This ensures the safety of researchers and the integrity of the experiments being conducted.

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Relevant academic research and scientific papers

Highly Efficient Binuclear Copper-catalyzed Oxidation of N,N-Dimethylanilines with O2

A binuclear copper-salicylate complex, [Cu(Sal)2(NCMe)]2 (Sal=salicylate), was found to be an active catalyst for the oxidation of N,N-dimethylanilines by O2, affording the corresponding N-methyl-N-phenylformamides as major products. The reactions were carried out with a O2 balloon and the S/C (substrate/catalyst ratio) of the model reaction could be up to 1×105, providing a practical and highly efficient catalytic protocol for accessing N-methyl-N-phenylformamides.

Photodriven Photocatalyst/Metal-Free Direct C-C/C-N Bond Formation: Synthesis of Indoles via EDA Complexes

The photodriven direct C-C/C-N bond formation initiated by electron donor-acceptor (EDA) complexes for the synthesis of indoles has been accomplished via [3+2] annulations of secondary arylamines with alkynes using IC4F9 as oxidants in the absence of any photocatalysts and metals. This green transformation exhibits the advantages of operational simplicity, good functional tolerances, and mild reaction conditions. The in situ generated EDA complexes derived from arylamines with alkynes were characterized by UV-vis absorption spectrometry and NMR titration experiments.

NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula (I) or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R1, R2, R3, R4 and R7 are defined in the specification, Z is SO or SO2, and Ar is an aromatic or heteroaromatic group as defined herein.

1H, 2H, 19F, 14N ENDOR and TRIPLE Resonance Investigations of Substituted Flavin Radicals in Their Different Protonation States

A variety of isotopically labelled and/or substituted flavins have been converted into their corresponding radical states.Cation and neutral radicals were generated chemically and anion radicals were obtained electrochemically.By performing ENDOR and TRIPLE resonance experiments, complete sets of hyperfine coupling constants including their signs were accessible.The hyperfine data allowed (a) identification of the radical state present, (b) information to be obtained about the preferred conformational arrangements of the substituents and (c) conclusions to be drawn about the influences of the substituents on the spin density distributions of the different radical states. - KEY WORDS: ENDOR, TRIPLE resonance spectroscopy; Flavin radicals; Electrochemical generation of radicals.