81067-37-0

Basic information

• Product Name: 1-BroMo-2,3,4-trichlorobenzene
• Synonyms: 1-BroMo-2,3,4-trichlorobenzene
• CAS NO: 81067-37-0
• Molecular Formula: C₆H₂BrCl₃
• Molecular Weight: 260.34308
• Product Categories: Aromatics, Intermediate
• Mol File: 81067-37-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-BroMo-2,3,4-trichlorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BroMo-2,3,4-trichlorobenzene(81067-37-0)
• EPA Substance Registry System: 1-BroMo-2,3,4-trichlorobenzene(81067-37-0)

Safety Data

• Hazardous Substances Data: 81067-37-0(Hazardous Substances Data)

Usage

Uses

1-Bromo-2,3,4-trichlorobenzene, is an intermediate used in different chemical synthesis. It can be used for the synthesis of monofluorinated polychlorinated biphenyls (fluoro-PCBs), for the use as internal standards for PCB analysis.

Upstream product

• 634-67-3 2,3,4-trichloroaniline 
• 87-61-6 1,2,3-trichlorobenzene 
• 915144-98-8 2,3,4-trichloro-1,5-phenylenebis(trimethylsilane) 
• 915144-97-7 trimethyl(2,3,4-trichlorophenyl)silane 
• 811720-26-0 1,5-dibromo-2,3,4-trichlorobenzene 

Downstream Products

• 2112-31-4 2,3,4-tri-chloro-benzonitrile 
• 887267-38-1 3-chloro-2,4-difluorobenzonitrile 
• 154257-75-7 2,4-difluoro-3-chlorobenzoic acid 
• 21928-51-8 5-bromo-1,2,3-trichloro-benzene 

Relevant articles and documents

Synthesis method of 3-chloro-2,4-difluorobenzoic acid

The invention relates to a synthesis method of 3-chloro-2,4-difluorobenzoic acid. The method comprises: taking 1,2,3-trichlorobenzene and N-bromosuccinimide to react, taking CuCN and 1-bromo-2,3,4-trichlorobenzene to react, taking the 1-bromo-2,3,4-trichlorobenzene and KF to react and taking 3-chloro-2,4-difluorobenzonitrile and sulfuric acid to react, so as to form the 3-chloro-2,4-difluorobenzoic acid. According to the synthesis method, synthesis reaction conditions are that a reaction is carried out at normal pressure and reaction temperature fluctuates between 0 and 250 DEG C; the obtained finished product is a light yellow powdery solid and the content is more than or equal to 99.0 percent; the total mol yield of the 3-chloro-2,4-difluorobenzoic acid can reach 61.5 percent; whole reaction conditions are moderate and the method is convenient to operate and control; pressure of waste gas, waste water and waste residues is relatively low so that industrial production is facilitated.

Tribromoisocyanuric acid in trifluoroacetic acid: An efficient system for smooth brominating of moderately deactivated arenes

Moderately deactivated arenes are efficiently brominated by the reaction with tribromoisocyanuric acid (0.34 mol equiv) in trifluoroacetic acid at room temperature in 48-85% isolated yield. This medium avoids the polybromination of the substrate, observed in the same reaction performed in 98% H 2SO4. Georg Thieme Verlag Stuttgart · New York.

Proton mobility in 2-substituted 1,3-dichlorobenzenes: "ortho" or "meta" metalation?

Nine 1,3-dichlorobenzene congeners were selected as model compounds to assess the relative rates of proton abstraction from 4- and 5-positions ("ortho" vs. "meta" metalation). Using lithium 2,2,6,6-tetramethylpiperidide as the basic reagent, the chlorine-adjacent 4-position underwent metalation exclusively. In contrast, attack at the chlorine-remote 5-posi" tion became significant even in the case of moderately sized 2-substituents (such as dimethylamino or ethyl) when secbutyllithium was employed. The "ortho/para" (4-/5-) ratios ranged from 80:20 to 65:35. The more pronounced "meta-orienting" effect of silicon as opposed to carbon substituents can be attributed to dissimilarities in the n polarization of the aromatic ring. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.