81153-44-8Relevant articles and documents
Synthesis and characterization of new 1H-pyrazolo[3,4-b]pyridine phosphoramidate derivatives
Pedrosa, Leandro F.,De Macedo, William P.,Furtado, Antonia C.R.,Guedes, Guilherme P.,Borges, Julio C.,Resende, Jackson A.L.C.,Vaz, Maria G.F.,Bernardino, Alice M.R.,De Souza, Marcos C.
, p. 38 - 50 (2014)
Twelve new 1H-pyrazolo[3,4-b]pyridine phosphoramidate derivatives were synthesized under mild conditions by nucleophilic aromatic substitution reaction of aminoalkylphosphoramidates over 4-Cl substituted pyrazolo[3,4-b]pyridine in good yields. The new com
Mass spectrometry of pyrazolo[3,4-b]pyrido[2′,3′-b]-1,6-naphthyridines and dipyrazolo[3,4-b];3′,4′-h]-1,6-naphthyridines
Khakwani, Samia,Aslam, Samina,Mussadiq, Sara,Shahi, Mehrzadi Noureen,Perveen, Najma,Rolim Bernardino, Alice M.,Khan, Misbahul Ain
, p. 2601 - 2604 (2016/10/17)
The mass spectra of several pyrazolo[3,4-b]pyrido[2′,3′-b]-1,6-naphthyridines and dipyrazolo[3,4-b];3′,4′-h]-1,6-naphthyridines are presented. The fragmentation is initiated by the elimination of CO molecule [m/z 28] followed by other fragments, such as h
The identification a novel, selective, non-steroidal, functional glucocorticoid receptor antagonist
Rimland, Joseph,Dunne, Angela,Hunjan, Suchete S.,Sasse, Rosemary,Uings, Iain,Montanari, Dino,Caivano, Matilde,Shah, Poonam,Standing, David,Gray, David,Brown, David,Cairns, William,Trump, Ryan,Smith, Paul W.,Bertheleme, Nicolas,D'Alessandro, Pier,Gul, Sheraz,Vimal, Mythily,Smith, David N.,Watson, Stephen P.
scheme or table, p. 2340 - 2343 (2010/08/22)
The identification of novel, potent, non-steroidal/small molecule functional GR antagonist GSK1564023A selective over PR is described. Associated structure-activity relationships and the process of optimisation of an initial HTS hit are also described.
