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N6-benzoyl-3'-O-t-butyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-adenosine is a sophisticated chemical compound derived from adenosine, a fundamental nucleoside constituent of DNA and RNA. This modified adenosine features a benzoyl group, a t-butyldimethylsilyl group, and a diMethoxytrityl group, which are chemical modifications that enhance its utility in various research applications. It is extensively utilized in biochemical and molecular biology research for the synthesis of nucleic acids and the investigation of adenosine analogs and their biological impacts.

81256-88-4

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81256-88-4 Usage

Uses

Used in Biochemistry and Molecular Biology Research:
N6-benzoyl-3'-O-t-butyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-adenosine is used as a research tool for the synthesis of nucleic acids due to its unique chemical modifications that facilitate specific reactions and analyses in the laboratory.
Used in the Study of Adenosine Analogs:
In the pharmaceutical and medicinal chemistry fields, N6-benzoyl-3'-O-t-butyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-adenosine serves as a key substance for examining the effects of adenosine analogs on biological systems, potentially leading to the development of new therapeutic agents.
Used in the Development of Novel Therapeutics:
N6-benzoyl-3'-O-t-butyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-adenosine's unique structure allows it to be explored for its potential in the creation of new drugs, particularly those that target adenosine receptors or pathways, which could have implications for treating various diseases and conditions.
Used in Chemical Synthesis Processes:
N6-benzoyl-3'-O-t-butyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-adenosine is utilized as an intermediate in the synthesis of more complex molecules, taking advantage of its modified functional groups to achieve specific chemical outcomes.
Used in Analytical Techniques:
N6-benzoyl-3'-O-t-butyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-adenosine can be employed in various analytical methods to detect and quantify adenosine or its derivatives in biological samples, providing insights into their roles and interactions within organisms.
Used in the Pharmaceutical Industry:
N6-benzoyl-3'-O-t-butyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-adenosine is used as a starting material or a building block in the development of pharmaceuticals that may have applications in treating conditions related to adenosine signaling.

Check Digit Verification of cas no

The CAS Registry Mumber 81256-88-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,2,5 and 6 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 81256-88:
(7*8)+(6*1)+(5*2)+(4*5)+(3*6)+(2*8)+(1*8)=134
134 % 10 = 4
So 81256-88-4 is a valid CAS Registry Number.

81256-88-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name N6-benzoyl-5'-O-DMT-3'-O-TBDMS-adenosine

1.2 Other means of identification

Product number -
Other names 5'-DMT-3'-TBDMS-Bz-rA

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:81256-88-4 SDS

81256-88-4Relevant academic research and scientific papers

CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF

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Paragraph 0101-0108, (2021/11/05)

Provided are a compound of formula (I), an optical isomer thereof, a pharmaceutically acceptable salt thereof, uses of said compound acting as a STING agonist.

CYCLIC DINUCLEOTIDES AS AGONISTS OF STIMULATOR OF INTERFERON GENE DEPENDENT SIGNALLING

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Paragraph 0296, (2018/09/26)

Disclosed herein are new cyclic dinucleotide compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of modulation of immune response to disease, and induce Stimulator of Interferon Genes (STING) dependent type I interferon production and co-regulated genes in a human or animal subject are also provided for the treatment diseases such as cancer, particularly metastatic solid tumors and lymphomas, inflammation, allergic and autoimmune disease, infectious disease, and for use as anti-viral agents and vaccine adjuvants.

Modified phosphotriester method for chemical synthesis of ribooligonucleotides. Part I. Synthesis of riboundecaadenylate and two fragments constituting the sequence of R-17 translation control signal

Sung, Wing L.,Narang, Saran A.

, p. 111 - 120 (2007/10/02)

A modified phosphotriester method has been succesfully applied for the chemical synthesis of ribooligonucleotides.The starting material is a fully protected ribomononucleoside containing a 3'-phosphotriester group 5.The coupling reaction is performed usin

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