812652-87-2

Upstream product

• 98-68-0 4-methoxy-phenyl-sulphonyl chloride 
• 142769-27-5 5,6-dimethoxy-1H-indole-3-carbaldehyde 
• 157670-07-0 2-azido-3-(3',4'-dimethoxyphenyl)acrylic acid methyl ester 
• 14430-23-0 5,6-dimethoxyindole 
• 28059-24-7 methyl 5,6-dimethoxy-1H-indole-2-carboxylate 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 88210-96-2 5,6-dimethoxyindole-2-carboxylic acid 

Downstream Products

• 812653-13-7 18-[5,6-dimethoxy-1-(4-methoxy-benzenesulfonyl)-1H-indol-3-yl]-octadecan-1-ol 
• 812653-12-6 16-[5,6-dimethoxy-1-(4-methoxybenzenesulfonyl)-1H-indol-3-yl]hexadecan-1-ol 

Relevant academic research and scientific papers

Effects of indole fatty alcohols on the differentiation of neural stem cell derived neurospheres

In a search for inducers of neuronal differentiation to treat neurodegenerative diseases such as Alzheimer's disease, a series of indole fatty alcohols (IFAs) were prepared, 13c (n = 18) was able to promote the differentiation of neural stem cell derived neurospheres into neurons at a concentration of 10 nM. Analysis of the expression of the Notch pathway genes in neurospheres treated during the differentiation phase with 13c (n = 18) revealed a significant decrease in the transcription of the Notch 4 receptor.