81267-11-0Relevant articles and documents
Enantioselective Synthesis of Isoflavanones by Catalytic Dynamic Kinetic Resolution
Qin, Tao,Metz, Peter
supporting information, p. 2981 - 2984 (2017/06/07)
A ruthenium-catalyzed asymmetric transfer hydrogenation of racemic isoflavanones with dynamic kinetic resolution yields virtually enantiopure isoflavanols as single diastereomers. Subsequent oxidation gives rise to isoflavanones in high enantiomeric purit
SYNTHESIS OF ISOFLAVANES AND INTERMEDIATES THEREOF
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Page/Page column 25, (2016/04/20)
Subject of the invention is a method for enantioselective production of an isoflavane from an isoflavone, comprising the steps: (a) selectively reducing the isoflavone, such that the 4-keto group of the isoflavone is converted to a 4-hydroxy group, and the 2,3-double bond of the isoflavone is converted to a 2,3-single bond, thereby obtaining a 4-hydroxy intermediate, and (b) reacting the 4-hydroxy intermediate with a chiral reagent, such that a chiral group is covalently attached to the C4-position of the 4-hydroxy intermediate, thereby obtaining a chiral intermediate. The invention also relates to intermediates of formulae (IV), (V), (VI) and (VII) obtainable in the inventive process.
Production of isoflavone derivatives
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Page/Page column 13, (2008/06/13)
Methods for the hydrogenation of isoflavones are described which provide access to workable quantities of isoflavan-4-ols, isoflav-3-enes, and isoflavans. The isoflavone derivatives can be obtained in high purity and in near quantitative yields whilst employing pharmaceutically acceptable reagents and solvents.
A Synthesis of Hydroxylated Isoflavylium Salts and Their Reduction Products
Liepa, Andris J.
, p. 2647 - 2655 (2007/10/02)
Phloroglucinol reacts with arylmalondialdehydes in the presence of hydrochloric acid to form 5,7-dihydroxyisoflavylium salts.Reduction of these salts can be utilized to form isoflav-2-enes, isoflav-3-enes or isoflavans.
