81471-22-9Relevant academic research and scientific papers
Catalyst-free system for sulfenylation of free (N-H) indoles with 2,2′-dithiosalicylic acid under alkaline conditions
Zhou, Xiaofei,Li, Xinhua
, p. 1241 - 1245 (2014)
A catalyst-free system for the sulfenylation of free (N-H) indoles using 2,2′-dithiosalicylic acid under alkaline conditions was developed in this study. This system provides a green, convenient and efficient method for sulfenylindole synthesis, with good yields and high selectivity. This simple synthesis was performed in a green solvent (isopropanol/H2O) under atmospheric and catalyst-free conditions. The procedure was suitable for use with N-unprotected indoles. An electrophilic coupling mechanism was proposed.
ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND ARTICLES OF MANUFACTURE FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES
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, (2021/01/22)
A compound can have a structure of Formula A, or derivative thereof, salt thereof, or stereoisomer thereof, or having any chirality at any chiral center, or tautomer, polymorph, solvate, or combination thereof: wherein ring A is a phenyl, indolyl, naphthyl, or benzothiazolyl; X is S, SO, or SO2; Y is a linker or bond; Z is CH, CR2, or N; Z1 is C or N to form an imidazopyridine; each Z2, Z3, or Z4 is independently CH, CR2, or N; each Z5 or Z6 is C or CH; each R1, R2, and R3 is independently a substituent, and at least one of R1, R2, or R3 is a substituent other than a hydrogen; m is 0, 1, 2, 3, or 4; and n is 0 or a positive integer. The compounds can have specific substituent patterns.
Metal free sulfenylation and bis-sulfenylation of indoles: Persulfate mediated synthesis
Prasad, Ch. Durga,Kumar, Shailesh,Sattar, Moh.,Adhikary, Amit,Kumar, Sangit
supporting information, p. 8036 - 8040 (2013/12/04)
A method which avoids metal and halogen for the synthesis of 3-arylthioindoles from indoles and diaryl disulfides using ammonium persulfate in methanol has been presented. Moreover, double C-H sulfenylation of indoles at 2 and 3-positions has also been ac
Cyclization of 2- and 3-indolylthiobenzoic, phenylacetic and nicotinic acids and esters to novel indole-containing tetracyclic ring systems
Hamel, Pierre,Girard, Mario,Tsou, Nancy N.
, p. 643 - 652 (2007/10/03)
A series of 2- and 3-indolylthio benzoic, phenylacetic and nicotinic acids or esters were cyclized under dehydrative conditions affording several tetracyclic indole-containing ketones, several of which constitute the first reported examples of novel ring systems, such as the [1]benzothiepino[2,3-b] and [3,2-b]indole and the pyrido[3'2':5,6] and [3'4':5,6]thiopyrano[2,3-b] and [3,2-b]indole as well as the [3'2':5,6] and [3'4':5,6][1,3]thiazino[3,2- a]indole ring systems.
