81532-35-6Relevant articles and documents
End-substituted homoallylic amine derivatives, a preparing method thereof and uses of the derivatives
-
Paragraph 0263-0265, (2018/03/24)
The invention belongs to the field of chemical medicines, and particularly relates to end-substituted homoallylic amine derivatives, a preparing method thereof and uses of the derivatives. In the method, the end-substituted homoallylic amine derivatives are prepared by allowing a 2-aza-allyl anion to participate, in a high regioselectivity manner, an allylation reaction catalyzed by iridium, and by an intramolecular 2-aza-Cope rearrangement reaction. The derivatives can be synthesized efficiently by the method. The method is simple, convenient and feasible. Prepared compounds have extremely high optical purity. The derivatives prepared by the method can be used for preparing Sertraline and Tametraline which are anti-depression medicines and some natural products.
Catalytic imine-imine cross-coupling reactions
Matsumoto, Masatoshi,Harada, Masashi,Yamashita, Yasuhiro,Kobayashi, Shu
supporting information, p. 13041 - 13044 (2015/01/16)
We report here efficient catalytic imine-imine cross-coupling reactions based on an umpolung strategy; an imine bearing a 9-fluorenyl moiety on its nitrogen atom, which acted as a nucleophile, reacted with another imine to afford an imine-imine cross-coupling adduct in high yield. Furthermore, a chiral guanidine acted as a chiral catalyst for these coupling reactions, and optically active 1,2-diamines were obtained in high yields with high enantioselectivities. This journal is
Chiral lanthanum(III)-binaphthyldisulfonate complexes for catalytic enantioselective strecker reaction
Hatano, Manabu,Hattori, Yasushi,Furuya, Yoshiro,Ishihara, Kazuaki
supporting information; experimental part, p. 2321 - 2324 (2009/10/02)
A catalytic enantioselective Strecker reaction catalyzed by novel chiral lanthanum(III)-binaphthyl disulfonate complexes was developed. The key to promoting the reactions was a semistoichiometric amount of AcOH or i-PrCO2H, which takes advantage of HCN ge
