81570-49-2

Basic information

• Product Name: 3-phenylbicyclo[2.2.1]heptane-2-carboxylic acid
• CAS NO: 81570-49-2
• Molecular Formula: C₁₄H₁₆O₂
• Molecular Weight: 216.2756
• Mol File: 81570-49-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 379°C at 760 mmHg
• Flash Point: 174.8°C
• Density: 1.19g/cm³
• Vapor Pressure: 2.03E-06mmHg at 25°C
• Refractive Index: 1.585
• CAS DataBase Reference: 3-phenylbicyclo[2.2.1]heptane-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenylbicyclo[2.2.1]heptane-2-carboxylic acid(81570-49-2)
• EPA Substance Registry System: 3-phenylbicyclo[2.2.1]heptane-2-carboxylic acid(81570-49-2)

Safety Data

• Hazardous Substances Data: 81570-49-2(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 637-44-5 phenylpropyolic acid 
• 542-92-7 cyclopenta-1,3-diene 
• 24161-43-1 methyl 3-phenylbicyclo<2.2.1>hepta-2,5-diene-2-carboxylate 
• 7299-58-3 phenylpropiolyl chloride 
• 1078-58-6 diphenylzinc 
• 17812-27-0 cis-5-norbornene-endo-2,3-dicarboxylic anhydride 
• 950-91-4 3-phenyl-2,5-norbornadiene-2-carboxylic acid 
• 6319-19-3 endo-5-carboxy-exo-6-phenylbicyclo<2.2.1>hept-2-ene 
• 6935-56-4 6-endo-hydroxy-5-exo-iodo-3-exo-phenylnorborn-2-endo-ylcarboxylic acid γ-lactone 
• 4360-47-8 cinnamonitrile 
• 14166-28-0 exo-bicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride 
• 6319-19-3 5-exo-carboxy-6-exo-phenylbicyclo<2.2.1>hept-2-ene 
• 140-10-3 (E)-3-phenylacrylic acid 

Downstream Products

• 28051-92-5 (2R)-endo-3-phenyl-endo-2-norbornanamine acid 
• 130686-28-1 1-((1S,2S,3S,4R)-3-Phenyl-bicyclo[2.2.1]heptane-2-carbonyl)-1,3-bis-((S)-1-phenyl-ethyl)-urea 

Relevant articles and documents

Decarbonylative cross-coupling of cyclic anhydrides: Introducing stereochemistry at an sp3 carbon in the cross-coupling event

Treatment of cyclic anhydrides with stoichiometric amounts of nickel-neocuproine complex generates alkylcarboxylato-nickelalactones upon extrusion of CO. These metalacycles undergo cross-coupling with arylzinc reagents. The generated CO is sequestered in situ by a nickel-dppb complex. The overall sequence effects a secondary sp3(electrophile)-sp2(nucleophile) cross-coupling and allows for control of stereochemistry during the bond-forming event. Copyright

A NEW CATALYTIC PROCESS BASED ON SEQUENTIAL INSERTION OF STRAINED OLEFINS AND CARBON MONOXIDE INTO Pd-C BONDS.

A palladium-catalyzed synthesis of carboxylic acids, esters and anhydrides by sequential alkylation, vinylation or arylation and carbonylation of strained olefins is reported.