81576-71-8Relevant articles and documents
Synthesis of Cyclic β-Amino Acid Esters from Methionine, Allylglycine, and Serine
Gardiner, James,Anderson, Kelly H.,Downard, Alison,Abell, Andrew D.
, p. 3375 - 3382 (2007/10/03)
Here we report a versatile ring-closing metathesis-based approach to 5-, 6-, and 7-membered cyclic β-amino esters starting with simple and readily available building blocks-methionine, allylglycine, and serine-where the nature of the amino acid determines
Synthesis of substituted cyclohexenyl-based β-amino acids by ring-closing metathesis
Abell, Andrew D.,Gardiner, James
, p. 3663 - 3666 (2007/10/03)
(equation presented) A versatile ring-closing metathesis (RCM) approach has been developed for the preparation of cis and trans cyclohexenyl-based β-amino acids that are either unsubstituted (3) or substituted (10 and 12) at the α-position.
NEW SYNTHESIS OF β-AMINO ACIDS BY NUCLEOPHILIC ADDITION OF ENOLATE ANIONS TO N-METHOXYCARBONYLIMINES GENERATED FROM α-METHOXY CARBAMATES.
Shono, Tatsuya,Kise, Naoki,Sanda, Fumio,Ohi, Satoru,Tsubata, Kenji
, p. 231 - 234 (2007/10/02)
The nucleophilic addition of enolate anions of alkyl acetates to N-methoxycarbonylimines generated from α-methoxy carbamates gave β-amino acid derivates (3) and enantioselective synthesis (72-90percentee) of 3 was achieved by using chiral 2-methyloxazolines instead of acetates.