91280-45-4

Upstream product

• 253454-00-1 (1S,2S)-Cyclohex-4-ene-1,2-dicarboxylic acid monomethyl ester 
• 100-51-6 benzyl alcohol 
• 81576-71-8 methyl (3R)-3-[(benzyloxy)carbonylamino]hex-5-enoate 
• 81576-72-9 (R)-3-Benzyloxycarbonylamino-hex-5-enoic acid 
• 83436-47-9 tert-butyl (R)-3-(((benzyloxy)carbonyl)amino)hex-5-enoate 
• 4841-84-3 dimethyl cis-1,2,3,6-tetrahydrophthalate 
• 31139-02-3 (1R,6S)-6-methoxycarbonyl-3-cyclohexene-1-carboxylic acid 
• 93603-11-3 1-methyl hydrogen 1,2-cis-1,2-cyclohex-4-ene dicarboxylate 
• 503167-42-8 (1S,6R)-6-Isocyanato-cyclohex-3-enecarboxylic acid methyl ester 
• 116733-43-8 (1R,6R)-6-(2-oxo-oxazolidine-3-carbonyl)-cyclohex-3-ene carboxylic acid methyl ester 
• 127474-54-8 (R)-2-(benzyloxycarbonylamino)pent-4-enoic acid 
• 475291-71-5 methyl (2R,3R)-2-allyl-3-[(benzyloxy)carbonylamino]hex-5-enoate 
• 91259-90-4 (1S,6R)-6-Benzyloxycarbonylamino-cyclohex-3-ene-1-carboxylic acid methyl ester 

Downstream Products

• 129313-92-4 (1R,6R)-6-benzyloxycarbonylaminocyclohex-3-enecarboxylic acid 
• 267230-45-5 (1R,2R)-2-aminocyclohexanecarboxylic acid methyl ester 
• 290838-42-5 methyl (1R,2R)-2-(((benzyloxy)carbonyl)amino)cyclohexane-1-carboxylate 
• 423760-29-6 (1R,2R)-2-methanesulfonylaminocyclohexanecarboxylic acid 
• 423760-31-0 (1R,2R)-2-Methanesulfonylamino-cyclohexanecarboxylic acid ((S)-1-hydroxymethyl-2-methyl-propyl)-amide 
• 423760-37-6 (1R,2R)-2-Methanesulfonylamino-cyclohexanecarbothioic acid [(S)-1-(tert-butyl-dimethyl-silanyloxymethyl)-2-methyl-propyl]-amide 
• 423760-35-4 (1R,2R)-2-Methanesulfonylamino-cyclohexanecarboxylic acid [(S)-1-(tert-butyl-dimethyl-silanyloxymethyl)-2-methyl-propyl]-amide 
• 91259-91-5 (1R,2R,4S,5S)-2-benzyloxycarbonylamino-4-iodo-7-oxo-6-oxabicyclo<3.2.1>octane 
• 129313-91-3 (1R,6R)-6-((S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionylamino)-cyclohex-3-enecarboxylic acid methyl ester 
• 129274-41-5 (1S,6S)-6-((S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionylamino)-cyclohex-3-enecarboxylic acid methyl ester 
• 1329602-72-3 C₂₀H₂₀N₂O₃S 
• 102508-02-1 (1R,6S)-6-Benzyloxycarbonylamino-cyclohex-3-enecarboxylic acid 
• 935470-08-9 ((1S,2R,5S)-7-Oxo-6-oxa-bicyclo[3.2.1]oct-2-yl)-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Second generation of fucose-based DC-SIGN ligands: Affinity improvement and specificity versus Langerin

DC-SIGN and Langerin are two C-type lectins involved in the initial steps of HIV infections: the former acts as a viral attachment factor and facilitates viral invasion of the immune system, the latter has a protective effect. Potential antiviral compounds targeted against DC-SIGN were synthesized using a common fucosylamide anchor. Their DC-SIGN affinity was tested by SPR and found to be similar to that of the natural ligand Lewis-X (LeX). The compounds were also found to be selective for DC-SIGN and to interact only weakly with Langerin. These molecules are potentially useful therapeutic tools against sexually transmitted HIV infection.

Synthesis of Cyclic β-Amino Acid Esters from Methionine, Allylglycine, and Serine

Here we report a versatile ring-closing metathesis-based approach to 5-, 6-, and 7-membered cyclic β-amino esters starting with simple and readily available building blocks-methionine, allylglycine, and serine-where the nature of the amino acid determines

Synthesis of substituted cyclohexenyl-based β-amino acids by ring-closing metathesis

(equation presented) A versatile ring-closing metathesis (RCM) approach has been developed for the preparation of cis and trans cyclohexenyl-based β-amino acids that are either unsubstituted (3) or substituted (10 and 12) at the α-position.

A New Ligand Scaffold for Catalytic Asymmetric Alkylzinc Additions to Aldehydes

matrix presented 1,3-Azole derivatives of 2-aminocyclohexanecarboxylic acid represent a new class of bidentate ligands for metal-mediated catalytic asymmetric synthesis. N-[2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)cyclohexyl]methanesulfonamide (6) is particu

CREATION OF NOVEL CHIRAL SYNTHONS WITH ENZYMES AND APPLICATIONS TO NATURAL PRODUCT SYNTHESIS. 15. EFFICIENT INTRODUCTION OF CHIRAL CENTERS INTO CYCLOHEXANE RING.

The chiral half-ester 2 obtained by asymmetric hydrolysis of the symmetric diester 1 with pig liver esterase has been shown to be a versatile synthon for various chiral cyclohexane derivatives.