81589-32-4

Basic information

• Product Name: Benzamide, 2-methoxy-N-[(4-methylphenyl)sulfonyl]-
• CAS NO: 81589-32-4
• Molecular Formula: C15H15NO4S
• Molecular Weight: 305.354
• Mol File: 81589-32-4.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Benzamide, 2-methoxy-N-[(4-methylphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 2-methoxy-N-[(4-methylphenyl)sulfonyl]-(81589-32-4)
• EPA Substance Registry System: Benzamide, 2-methoxy-N-[(4-methylphenyl)sulfonyl]-(81589-32-4)

Safety Data

• Hazardous Substances Data: 81589-32-4(Hazardous Substances Data)

Upstream product

• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 
• 135-02-4 ortho-anisaldehyde 
• 21615-34-9 2-Methoxybenzoyl chloride 
• 92755-81-2 N-bromo-p-toluenesulfonamide 
• 46270-50-2 1-(2-methoxyphenyl)-2-nitroethan-1-one 
• 579-75-9 2-Methoxybenzoic acid 
• 21849-40-1 dibromamine-T 
• 41085-71-6 bromamine T 
• 38316-04-0 1-(2-methoxy-phenyl)-2-nitro-ethanol 
• 70-55-3 toluene-4-sulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 98-88-4 benzoyl chloride 
• 67-56-1 methanol 
• 6971-74-0 N-benzoyl-p-toluenesulfonamide 

Downstream Products

• 1043527-79-2 C₁₅H₁₄ClNO₃S 
• 1638287-07-6 2,6-dimethoxy-N-(4-methylbenzenesulfonyl)benzenecarboxamide 
• 221667-31-8 N-{[4-(cyclopropylcarbamoyl)phenyl]sulfonyl}-2-methoxybenzamide 
• 1369576-88-4 3-methoxy-4'-methyl-N-(4-methylbenzenesulfonyl)biphenyl-2-carboxamide 

Relevant articles and documents

Improvements of C-H Radio-Iodination of N-Acylsulfonamides toward Implementation in Clinics

An improved protocol to perform C-H radio-iodination is described. These new conditions allow rapid and clean formation of radio-iodinated N-acylsulfonamides using [125 I]NIS and catalytic amounts of palladium acetate and para-toluenesulfonic a

Preparation method of benzoylsulfamoyl benzamide and preparation intermediate

The invention provides a preparation method of benzoylsulfamoyl benzamide. The method comprises the following steps: reacting a sulfamoyl benzoic acid compound as shown in formula (I) with pivaloyl chloride so as to generate an anhydride compound as shown in formula (II), and reacting the anhydride compound with amine. In the formulas, R1 is hydrogen, halogen, a C1-10 alkyl group, a C1-10 alkoxy group, a C3-8 cycloalkyl group, a C3-8 cycloalkoxy group, a halogenated C1-10 alkyl group, a halogenated C1-10 alkoxy group, a halogenated C3-8 cycloalkyl group or a halogenated C3-8 cycloalkoxy group,and R2 and R3 each independently represent hydrogen, a C1-10 alkyl group, or a C3-8 cycloalkyl group. The invention also relates to compounds as shown in the formula (II) and application of the compounds as intermediates for the preparation of compounds as shown in formula (III).

Formation of esters and amides via metal-free Csp2-Csp3 bond cleavage of α-nitro ketone: Mechanistic insight to the reaction pathway

A catalyst free protocol for hucleophilic Csp2-Csp3 bond cleavage of a-nitroketone has been achieved for the formation of C-O and C-N bond. A series of differently substituted a-nitroketones could be selectively cleaved and converted into corresponding esters and tosylamides in presence of alcohols and bromamine-T respectively. Mechanism of the C-C bond cleavage has been proposed by identifying different reaction intermediates using IR and NMR spectroscopic methods.