81635-83-8Relevant academic research and scientific papers
4-ALKYL-1,4-DIHYDROPYRIDINES WITH PAF-ANTAGONIST ACTIVITY
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, (2008/06/13)
4-alkyl-1,4-dihyropyridines, with PAF-antagonist activity, of formula (I) wherein R is saturated C 1-C 4, R' is saturated C. sub.1-C. sub.6 alkyl which may be interrupted by an oxygen atom, or 2-tetrahydrofurfuryl and R 2 is saturated C 1-C 4 or phenyl, t
4-Alkyl-1,4-dihydropyridines Derivatives as Specific PAF-Acether Antagonists
Sunkel, Carlos E.,Casa-Juana, Miguel Fau de,Santos, Luis,Gomez, M. Mar,Villarroya, Mercedes,et al.
, p. 3205 - 3210 (2007/10/02)
A new series of 4-alkyl-1,4-dihydropyridines (1,4-DHP) were synthesized and evaluated for their ability to inhibit washed rabbit platelet aggregation induced by PAF-acether (1-O-hexadecyl/octadecyl-2-O-acetyl-sn-glycero-3-phosphorylcholine) and to reverse
Esters of 1,4-dihydropyridine-3- and -3,5-carbothiolic acids
Vigante,Ozols,Dubur,Beilis,Belash,Prezhdo
, p. 170 - 178 (2007/10/02)
Methods for the preparation of esters of 1,4-dihydropyridine-3- and -3,5-carbothiolic acids were developed, and their structure and reactivity were studied. A comparative analysis was made of the spectroscopic characteristics of sulfur-containing esters of the 1,4-dihydropyridine series and their oxygen analogs. More strongly expressed electron-acceptor properties of the COSAlk groupings as compared with alkoxycarbonyl substituents were observed.
