81664-99-5

Basic information

• Product Name: 1,1,1,2,2,3,3-heptafluoro-4-phenylbutane
• Synonyms: 1,1,1,2,2,3,3-heptafluoro-4-phenylbutane
• CAS NO: 81664-99-5
• Molecular Weight: 260.154
• Mol File: 81664-99-5.mol

Chemical Properties

• CAS DataBase Reference: 1,1,1,2,2,3,3-heptafluoro-4-phenylbutane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1,2,2,3,3-heptafluoro-4-phenylbutane(81664-99-5)
• EPA Substance Registry System: 1,1,1,2,2,3,3-heptafluoro-4-phenylbutane(81664-99-5)

Safety Data

• Hazardous Substances Data: 81664-99-5(Hazardous Substances Data)

Upstream product

• 1589-82-8 phenylmagnesium bromide 
• 336-59-4 heptafluorobutyric anhydride 
• 780-24-5 dibenzylmercury(II) 
• 2117-39-7 benzylmercury(II) chloride 
• 6921-34-2 benzylmagnesium chloride 
• 75-61-6 dibromodifluoromethane 
• 100-44-7 benzyl chloride 
• 1514-87-0 metyhyl chlorodifluoroacetate 
• 100-39-0 benzyl bromide 

Relevant articles and documents

Synthesis of functionalized long-chain perfluoroalkanes from methyl halodifluoroacetates: a process of difluorocarbene insertion into copper-carbon bonds

Treatment of XCF2CO2Me (X = Cl, Br) with organic halides in the presence of KF and catalytic amounts of CuI at 80-120 deg C for 3-8 h in DMF gave long-chain perfluoroalkylated compounds which are considered to be former by the insertions of CF2(..) into carbon-copper bonds.

The reactions of copper-dibromodifluoromethane-amide systems with alcohols

1,1,1-Trifluoro-2-arylethanes can be prepared by the trifluoromethyldehydroxylation of benzyl alcohols using the copper-dibromodifluoromethane-amide reaction system, although the yields are low.The mechanism of the reaction may involve chelation of the substrate to copper so that α-substituted benzyl alcohols and other alcohols are unreactive.

Reaction of Bis(heptafluorobutyryl) Peroxide with Carbanions and a Thiolate Anion

In the reaction of bis(heptafluorobutyryl) peroxide with carbanions and a thiolate anion, two types of reactions were observed; one is an electron transfer reaction to give perfluoropropylated compounds and the other is a nucleophilic substitution.

Perfluoroalkylations of Carbanions with (Perfluoroalkyl)-phenyliodonium Triflates (FITS Reagents)

FITS reagents reacted with primary alkylmagnesium halides in THF at -78 deg C to give the corresponding perfluoroalkyl(Rf)-alkanes in moderate to good yields.But an alkyl-lithium or -copper gave a poor yield of the Rf-product.The rea

PERFLUOROALKYLATION OF CARBANIONS

A successful perfluoroalkylation of various carbanions by the use of perfluoroalkylphenyliodonium trifluoromethanesulfonate (FITS) was described.The reactivity of other perfluoroalkyliodonium salt was also examined.