81819-14-9

Upstream product

• 14224-99-8 2-methyl-4,5-diphenyloxazole 
• 119-53-9 2-hydroxy-2-phenylacetophenone 

Downstream Products

• 96972-67-7 (4,5-diphenyl-oxazol-2-ylmethyl)-phosphonic acid diethyl ester 
• 138129-07-4 [3-(4,5-Diphenyl-oxazol-2-ylmethyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid ethyl ester 
• 81819-15-0 pentaethylene glycol mono-2-methyl-4,5-diphenyloxazole ether 
• 136451-77-9 methyl <3-<(4,5-diphenyl-2-oxazolyl)methoxy>phenoxy>acetate 
• 136451-69-9 methyl 3-<3-<(4,5-diphenyl-2-oxazolyl)methoxy>phenyl>-propanoate 
• 65913-22-6 2-(4,5-diphenyloxazol-2-yl)acetonitrile 
• 170305-67-6 (2'S)-<1-(4,5-Diphenyl-1,3-oxazol-2-ylmethyl)pyrrolidin-2'-yl>methanol 
• 328000-89-1 4,5-Diphenyl-2-phthalimidomethyl-1,3-oxazole 
• 187993-41-5 (1R)-1-(4,5-diphenyloxazol-2-yl)methylamino-5-t-butyldiphenylsilyloxy-1,2,3,4-tetrahydronaphthalene 
• 187993-43-7 (1R)-1-(4,5-diphenyloxazol-2-yl)methyloxy-5-t-butyldiphenylsilyloxy-1,2,3,4-tetrahydronaphthalene 
• 147594-34-1 (E)-methyl <3-<2-cyano-2-(4,5-diphenyl-2-oxazolyl)ethenyl>phenoxy>acetate 
• 147594-36-3 methyl <3-<2-cyano-2-(4,5-diphenyl-2-oxazolyl)ethyl>phenoxy>acetate 
• 110703-64-5 [3-(4,5-Diphenyl-oxazol-2-ylmethyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid 
• 136451-71-3 methyl 3-[4-[(4,5-diphenyl-2oxazolyl)methoxy]phenyl]propanoate 

Relevant academic research and scientific papers

Synthesis of extended oxazoles II: Reaction manifold of 2-(halomethyl)-4,5-diaryloxazoles

2-(Halomethyl)-4,5-diphenyloxazoles are effective, reactive scaffolds which can be utilized for synthetic elaboration at the 2-position. Through substitution reactions, the chloromethyl analogue is used to prepare a number of 2-alkylamino-, 2-alkylthio-, and 2-alkoxy-(methyl) oxazoles. The 2-bromomethyl analogue offers a more reactive alternative to the chloromethyl compounds and is useful in the C-alkylation of a stabilized (malonate) carbanion as exemplified by a concise synthesis of Oxaprozin.

HEPATITIS C VIRUS INHIBITORS

The present disclosure is generally directed to antiviral compounds, and more specifically directed to compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such compounds, and methods for inhibiting the function of the NS5A protein

[2(4,5-diaryl-2 oxazoyl substituted phenoxy alkanoic acid and esters

Oxazole derivatives having Formula I or II are disclosed which are useful as inhibitors of mammalian blood platelet aggregation. STR1 Formula I and Formula XIX compounds are those wherein n is 7-9 and R is hydrogen or lower alkyl. Formula II compounds are those wherein R is hydrogen, lower alkyl or together with CO2 is tetrazol-1-yl; R1 is phenyl or thienyl; X is a divalent connecting group selected from the group consisting of CH2 CH2, CH=CH, and CH2 O; Y is a divalent connecting group attached to the 3 or 4 phenyl position selected from the group consisting of OCH2, CH2 CH2 and CH=CH. Formula XX compounds are those wherein the OCH2 CO2 R moiety is attached to the 3 or 4 phenyl position and R is hydrogen or lower alkyl.