81963-43-1

Upstream product

• 81963-42-0 phenylhydrazone of trifluoroacetaldehyde 
• 100-63-0 phenylhydrazine 

Downstream Products

• 81963-46-4 5-Butoxy-1-phenyl-3-trifluoromethyl-4,5-dihydro-1H-pyrazole 
• 98664-44-9 4,5-dimethoxycarbonyl-1-phenyl-3-trifluoromethylpyrazole 
• 81963-54-4 Methyl 1-phenyl-3-trifluoromethylpyrazole-4-carboxylate 
• 81963-52-2 1,5-Diphenyl-3-trifluoromethyl-4,5-dihydro-1H-pyrazole-4-carboxylic acid methyl ester 
• 81963-51-1 2,4-Diphenyl-5-trifluoromethyl-3,4-dihydro-2H-pyrazole-3-carboxylic acid methyl ester 
• 81963-53-3 1-phenyl-3-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid methyl ester 
• 81963-45-3 5-methoxycarbonyl-1-phenyl-3-trifluoromethyl-2-pyrazoline 
• 81963-50-0 5-Methyl-1-phenyl-3-trifluoromethyl-4,5-dihydro-1H-pyrazole-4-carboxylic acid methyl ester 
• 81963-49-7 4-Methyl-2-phenyl-5-trifluoromethyl-3,4-dihydro-2H-pyrazole-3-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Cycloadditions of N-Aryl-C-(Trifluoromethyl)nitrilimines with Dimethyl Fumarate and Maleate

The cycloadditions of N-aryl-C-(trifluoromethyl)nitrilimines 1, generated in situ from various precursors, with dimethyl fumarate and maleate are described.N-Aryltrifluoroacetohydrazonoyl bromides 2 reacted with fumarate in the presence of triethylamine to give the trans-4,5-dimethoxycarbonylpyrazolines 4 whereas the reactions with maleate afforded the 4,5-dimethoxycarbonylpyrazoles 5 as well as 4.In the reactions with the chloride 6 under the more drastic conditions, both fumarate and maleate gave the pyrazole 5a.From thermolysis of the oxadiazaphosphole 8, thetrans-pyrazoline 4a was formed in both cases of fumarate and maleate.The preparation of the cis-pyrazoline 9 was attempted from 8 and maleic anhydride but 9 was found to be so unstable as to be epimerized under the mild conditions.

PREPARATION OF TRIFLUOROACETONITRILE PHENYLAMINE AND ITS REACTIONS WITH SOME DIPOLAROPHILES

Trifluoroaceto-N-phenylhydrazonoyl halides, the precursors of trifluoroacetonitrile phenylamine, prepared by halogenation of trifluoroacetaldehyde phenylhydrazon, react with various olefins and acetylenes in the presence of triethylamine to give 3-trifluo