819813-71-3

Basic information

• Product Name: Benzoic acid, 3,4-bis(2-methoxyethoxy)-
• CAS NO: 819813-71-3
• Molecular Formula: C13H18O6
• Molecular Weight: 270.282
• Mol File: 819813-71-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3,4-bis(2-methoxyethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3,4-bis(2-methoxyethoxy)-(819813-71-3)
• EPA Substance Registry System: Benzoic acid, 3,4-bis(2-methoxyethoxy)-(819813-71-3)

Safety Data

• Hazardous Substances Data: 819813-71-3(Hazardous Substances Data)

Upstream product

• 99-50-3 3,4-Dihydroxybenzoic acid 
• 3943-89-3 Ethyl protocatechuate 
• 183322-16-9 3,4-bis(2-methoxyethoxy)benzoic acid ethyl ester 
• 121-33-5 vanillin 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 80407-64-3 3,4-bis(2-methoxyethoxy)benzaldehyde 
• 2150-43-8 3,4-dihydroxybenzoic acid methyl ester 
• 179688-14-3 methyl 3,4-bis{[2-(methyloxy)ethyl]oxy}benzoate 
• 627-42-9 2-chloroethyl methyl ether 

Downstream Products

• 80407-68-7 3,4-bis(2-methoxyethoxy)-benzonitrile 
• 236750-65-5 4,5-bis(2-methoxyethoxy)-2-nitrobenzonitrile 
• 1418289-91-4 3,4-bis(2-methoxyethoxy)-benzamide 
• 950596-58-4 2-amino-4,5-bis-(2-methoxyethoxy)-benzonitrile 
• 950596-59-5 N′-[2-cyano-4,5-{bis(2-methoxyethoxy)phenyl}]-N,N-dimethylformamidine 
• 183321-74-6 erlotinib 
• 183319-69-9 erlotinib hydrochloride 
• 179688-29-0 6,7-bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one 
• 501684-22-6 methyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 
• 476168-17-9 2-amino-4,5-bis-(2-methoxyethoxy)-benzoic acid methyl ester 
• 179688-14-3 methyl 3,4-bis{[2-(methyloxy)ethyl]oxy}benzoate 
• 183322-16-9 3,4-bis(2-methoxyethoxy)benzoic acid ethyl ester 
• 179688-26-7 2-nitro-4,5-bis(2-methoxyethoxy)benzoic acid ethyl ester 
• 1447828-82-1 N¹-(6,7-bis(2-methoxyethoxy)quinazolin-4-yl)-N³,N³-bis(2-chloroethyl)benzene-1,3-diamine hydrochloride 

Relevant articles and documents

KINASE INHIBITORS

Compounds that inhibit kinase Lck or Btk, pharmaceutically acceptable salts, hydrides, stereoisomers and pharmaceutical compositions thereof are disclosed.

Bacterial Cell Growth Inhibitors Targeting Undecaprenyl Diphosphate Synthase and Undecaprenyl Diphosphate Phosphatase

We synthesized a series of benzoic acids and phenylphosphonic acids and investigated their effects on the growth of Staphylococcus aureus and Bacillus subtilis. One of the most active compounds, 5-fluoro-2-(3-(octyloxy)benzamido)benzoic acid (7, ED50

An improved convergent approach for synthesis of erlotinib, a tyrosine kinase inhibitor, via a ring closure reaction of phenyl benzamidine intermediate

An improved convergent and economical method has been developed for the synthesis of erlotinib, a 4-anilinoquinazoline and an EGFR-tyrosine kinase inhibitor for treatment of non-small-cell lung cancer. The final two steps for the formation of this 4-anilinoquinazoline from suitable 2-aminobenzonitrile intermediate and 3-ethynylaniline were modified and were performed in a simple one-pot reaction. The ring-closing mechanism for the formation of erlotinib from the suitable formamidine intermediate and 3-ethynylaniline was investigated and determined to proceed via the formation of phenyl benzamidine intermediate rather than involving Dimroth rearrangement reported earlier. The new benzamidine intermediate was isolated for the first time and characterized. Copyright