82228-11-3Relevant articles and documents
Total Synthesis of a Hyperbranched N-Linked Hexasaccharide Attached to ATCV-1 Major Capsid Protein without Precedent
Wang, Yong-Shi,Wu, Yong,Xiong, De-Cai,Ye, Xin-Shan
supporting information, p. 42 - 48 (2019/01/04)
The N-glycans attached to some chloroviruses comprise a hyperbranched core structure without precedent. We are interested in the chemical synthesis of the hexasaccharide attached to ATCV-1 (Acanthocystis turfacea Chlorella virus 1) for its distinct structure. After exploring four routes, the target hexasaccharide 2 was successfully synthesized for the first time in overall 10% yield over 8 steps from thioglycoside building blocks. This synthetic protocol is characterized by the three-component one-pot glycosylation and the regioselective glycosylation reactions. The disclosed synthetic approach to this new type of N-glycans will facilitate the in-depth understanding of their biological functions.
SYNTHESIS OF A BRANCHED D-GLUCOTETRAOSE, THE REPEATING UNIT OF THE EXTRACELLULAR POLYSACCHARIDES OF Grifola umbellate, Sclerotinia libertiana, Porodisculus pendulus, AND Schizophyllum commune FRIES
Ogawa, Tomoya,Kaburagi, Toshiaki
, p. 53 - 64 (2007/10/02)
The synthesis of D-glucotetraose, 3-O--6-O-β-D-glucopyranosyl-α (and β)-D-glucopyranose, the repeating unit of the extracellular polysaccharides of Grifora umbellata, Sclerotinia libertiana, Porodisculus pendulus, and Schizophyllum commune Fries, is described.