82231-91-2Relevant academic research and scientific papers
Some reactions of 4-ethoxycarbonyl - And 4-chlorocarbonyl-3-chloro-5,6 diphenylpyridazines, synthesis of some fused pyridazines
Shalaby
, p. 401 - 412 (2007/10/03)
REACTION of compound 1 with benzhydrazide in refluxing 1-butanol yielded triazolo[4,3-b] pyridazine 2. On treatment of 1 with sodium azide in dimethylformamide produced pyrazolopyridazine 3. However, reaction of 1 with o-aminothiophenol gave thiazepinopyridazine 4. While, treatment of 1 with 2-aminoethanol and 2-mercaptoethanol gave the pyridazine derivatives 5 and 6. respectively. Moreover, treatment of 1 and 9 or 10 with ethylenediamine afforded pyridazino[4,3-f]diazepines 7 and 11, respectively. Also, compound 9 reacted with 2-aminoethanol forming pyridazino[4,3-f]oxazepine derivative 12. While reaction of 9 or 10 with o-phenylenediamine, o-aminophenol and o-aminothiophenol produced diazepino-, oxazepino- and thiazepinopyridazine derivatives 13-15, respectively. Hydrazinolysis of 9 afforded the pyrazolopyridazine 16. Grignard reaction on 13 using phenylmagnesium bromide and benzylmagnesium chloride gave pyridazinodiazepine derivatives 17 and 18, respectively. However, sulfuration of 11 and 16 with phosphorus pentasulfide gave the thionated products 19 and 20, respectively. Compound 20 was trapped by methylation with methyliodide to give 21.
Synthesis of Some New Fused Pyridazine Systems form 4-Acetyl-5,6-diphenylpyridazin-3(2H)-one
Ismail, Mohamed Fekry,Derbala, H.A.Y.,Abul-Yazeed, H.S.E.
, p. 787 - 790 (2007/10/03)
Some fused pyridazine systems were readily prepared starting from 4-acetyl-5,6-diphenylpyridazin-3(2H)-one, 1, and its thione derivative 6.Treatment of 1 with aromatic aldehydes in refluxing ethanol in the presence of a catalytic amount of piperidine resu
Action of Acrylonitrile on 4-Cyano- and 4-Carbethoxy Pyridazin-3(2H)-ones and their 3-Mercapto Derivatives. A Novel Synthesis of Pyrano and Thiinopyridazines
Shams, N. A.,Kaddah, A. M.,Enayat, E. I.,Shalaby, Alyaa A.,Youssef, A. M.
, p. 757 - 762 (2007/10/02)
Reaction of acrylonitrile with 4-cyano-5,6-diphenylpyridazin-3(2H)-one and 3(2H)-thione derivative (1a, b) at elevated temperature gave 7H-5-amino-6-cyano-3,4-diphenylpyrano and thiino pyridazines (2a, b), respectively.However, the reaction of 4-c
Herbicidal and plant growth regulant diphenylpyridazinones
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, (2008/06/13)
Novel compounds of the general formula STR1 as well as novel compositions thereof and methods of using same are described. These compounds have been found to be valuable for controlling, modifying and inhibiting the growth of plants.
