82683-51-0

Basic information

• Product Name: SPIRO[4.5]DECANE-7,9-DIONE
• Synonyms: SPIRO[4.5]DECANE-7,9-DIONE
• CAS NO: 82683-51-0
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.22
• Mol File: 82683-51-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 314°C at 760 mmHg
• Flash Point: 117.5°C
• Appearance: /
• Density: 1.1g/cm³
• Vapor Pressure: 0.00048mmHg at 25°C
• Refractive Index: 1.5
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: SPIRO[4.5]DECANE-7,9-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: SPIRO[4.5]DECANE-7,9-DIONE(82683-51-0)
• EPA Substance Registry System: SPIRO[4.5]DECANE-7,9-DIONE(82683-51-0)

Safety Data

• Hazardous Substances Data: 82683-51-0(Hazardous Substances Data)

Usage

General Description

Spiro[4.5]decane-7,9-dione is a type of organic compound classified under the spiroketal group. As a synthetic compound, its most common use is in research laboratories. Unlike simple ketals, which are typically produced by the reaction of an alcohol and a ketone, spiroketals like Spiro[4.5]decane-7,9-dione are created through more complex chemical reactions. Its distinctive structure, in which two cyclic structures of different sizes share a single atom, has generated significant interest among chemists. Its exact physical and chemical properties, such as solubility, melting point, and reactivity, may vary depending on specific conditions or its potential functionalized derivatives.

InChI:InChI=1/C10H14O2/c11-8-5-9(12)7-10(6-8)3-1-2-4-10/h1-7H2

Upstream product

• 120-92-3 cyclopentanone 
• 823-91-6 1-cyclopentenylpropan-2-one 
• 933-02-8 1-cyclopentylidenepropan-2-one 
• 105-53-3 diethyl malonate 
• 141-52-6 sodium ethanolate 
• 67570-15-4 1-(2-Methylprop-2-enyl)cyclopentan-1-ol 
• 38134-31-5 1-(1-Hydroxycyclopentyl)propan-2-on 

Downstream Products

• 16713-66-9 1,1-cyclopentanediacetic acid 
• 1239619-84-1 9-(benzhydrylamino)-spiro[4.5]dec-8-en-7-one 

Relevant articles and documents

FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS ROR GAMMA MODULATORS

The present invention provides fused thiophene and thiazole derivatives of formula (I), which may be therapeutically useful, more particularly as RORγ modulators; in which R1, R2, R3, R4, R5, R6, R7, X1, X2, L, m, n and ring A have the meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention of diseases or disorders, in particular their use in disease(s) or disorder(s) where there is an advantage in modulating RORγ receptor. The present invention also provides preparation of the compounds and pharmaceutical formulations comprising at least one of the fused thiophene and thiazole derivatives of formula (I), together with a pharmaceutically acceptable carrier, diluent or excipient therefor.

Chemistry of free cyclic vicinal tricarbonyl compounds ('1,2,3-triones'). Part 1. Reaction of diazomethane and its derivatives with 5,5-dimethylcyclohexane-1,2,3-trione (='oxo-dimedone') and related cyclohexane-1,2,3-triones

Interactions of diazomethane and of its derivatives as typical nucleophiles with cyclic 1,2,3-triones as efficient electrophiles lead to different results: a) formation of oxiranes (C,O insertion under loss of N2), b) nucleophilic addition yiel